The goal of this study was to examine the impact using additional aluminum (Al) and copper (Cu) filters on radiation dose during adult chest x-ray examination. Adult phantoms without with different slabs animal fat were used for simulating underweight, overweight, obese patients, respectively. Phantoms examined various levels extra Al Cu filtering over a range exposure parameters. A area produc...

The impact of spectral filtration in digital ('cine') acquisition was investigated using a flat panel cardiac interventional X-ray imaging system. A 0.1-mm copper (Cu) and 1.0-mm aluminium (Al) filter added to the standard acquisition mode created the filtered mode for comparison. Image sequences of 35 patients were acquired, a double-blind subjective image quality assessment was completed and ...

Although pediatric doses for biotherapeutics are often based on patients' body weight (mg/kg) or body surface area (mg/m²), linear body size dose adjustment is highly empirical. Growth and maturity are also important factors that affect the absorption, distribution, metabolism and excretion (ADME) of biologics in pediatrics. The complexity of the factors involved in pediatric pharmacokinetics l...

The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...

The relative bioavailability of the test (generic) product 2 × 25 mg baclofen tablets, with respect to the reference product, Lioresal® 2 × 25 mg tablets (baclofen; Squibb) was determined in a single-blind, single dose, randomised, crossover study. The mean values for the variable Cmax were 737.6 ng/ml for the reference and 739.5 ng/ml for the test product. The mean values for the variable AUC ...

BACKGROUND AND PURPOSE Since the introduction of flat panel detector-equipped C-arms, the use of flat panel detector CT (FPCT) in the neuroradiologic angiography suite has become more frequent. This examination implicates its own specific radiation exposure. We used the CT dose index (CTDI) concept and adapted it to the special FPCT geometry to provide a consistent comparison with multisection ...

Pediatric cardiac catheterization covers both diagnostic and therapeutic procedures that range from simple to complex and can subject pediatric patients to varying radiation doses. There is limited information on radiation doses delivered by pediatric cardiac catheterization procedures and there is no recommended reference dose levels established yet. The study aims to determine the variation i...

Introduction The purpose was to determine if an age based, local diagnostic reference level for paediatric skeletal surveys could be established using retrospective data. Methods All children below two years of referred a primary survey as result suspected physical abuse during 2017 or 2018 (n = 45) were retrospectively included from large Danish university hospital. protocol total 33 images. D...

Introduction: The dosimetric characteristics of patch sources including 32P, 90Y, 188Re and 166Ho, which are employed for radionuclide skin therapy, have been evaluated in current study Materials and Methods: The patch sources understudy were modeled by MCNPX Monte Carlo code and corresponding depth dose distribution, transverse dose profile and isodose curves...