نتایج جستجو برای: dose fdg
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Purpose: Assessing clinical activity ofmolecularly targeted anticancer agents, especially in the absence of tumor shrinkage, is challenging. To evaluate on-treatment 18F-fluorodeoxyglucose (FDG) and/or 18Ffluorodeoxythymidine (FLT) positron emission tomography (PET) for this purpose, we conducted a prospective multicenter trial assessing PET response rates and associations with progression-free...
BACKGROUND After the diagnosis Non-Small-Cell Lung Carcinoma (NSCLC) has been established, consideration must turn toward the stage of disease, because this will impact directly on management and prognosis. Staging is used to predict survival and to guide the patient toward the most appropriate treatment regimen or clinical trial. Distinguishing malignant involvement of the mediastinal lymph no...
UNLABELLED AKT (a serine/threonine-specific protein kinase) regulates many cellular processes contributing to cytotoxic drug resistance. This study's primary objective examined the relationship between GSK2141795, an oral, pan-AKT inhibitor, and (18)F-FDG PET markers of glucose metabolism in tumor tissue to determine whether (18)F-FDG PET could be used to guide personalized dosing of GSK2141795...
Purpose: Assessing clinical activity ofmolecularly targeted anticancer agents, especially in the absence of tumor shrinkage, is challenging. To evaluate on-treatment 18F-fluorodeoxyglucose (FDG) and/or 18Ffluorodeoxythymidine (FLT) positron emission tomography (PET) for this purpose, we conducted a prospective multicenter trial assessing PET response rates and associations with progression-free...
BACKGROUND PET using 18fluorodesoxyglucose (FDG) may offer the possibility of differentiating vital from necrotic residual masses. PATIENTS AND METHODS Seventeen patients with HD and 17 patients with NHL underwent FDG-PET following therapy. According to staging by routine methods at diagnosis, 7 patients presented stage I, 13 stage II, 5 stage III, and 9 stage IV. A dose of 250-400 MBq FDG wa...
UNLABELLED The aim of our study was to evaluate prospectively the diagnostic performance and prognostic significance of (18)F-FDG PET/CT in comparison with (123)I-metaiodobenzylguanidine ((123)I-MIBG) imaging in patients with high-risk neuroblastoma. METHODS Twenty-eight patients with refractory or relapsed high-risk neuroblastoma (16 male and 12 female patients; age range, 2-45 y; median age...
Received 1/8/2002; accepted 1/17/2002. For correspondence or reprints contact: Pan-Fu Kao, M.D., Department of Nuclear Medicine, Chang Gung Memorial Hospital and Chang Gung University, 199 Tung Hwa North Road, Taipei 105, Taiwan, R.O.C. Tel: (886)3-3281200 ext. 2622, Fax: (886)3-3282619, E-mail: [email protected] Background: Fluor ine-18-2-deoxy-D-glucose ([F]FDG) has been widespread use...
The aim of this study was to investigate the relationship between standardized uptake value (SUV), obtained from [18F]fluorodeoxyglucose positron emission tomography (FDG PET), and treatment response and survival of inoperable NSCLC patients treated with high dose radiotherapy. Fifty-one patients were included, recording stage, performance, weight loss, tumour volume, histology, lymph node invo...
BACKGROUND Radiotherapy of skin cancer in a previously irradiated area is a challenging task with regard to cumulative total dose and consecutive normal tissue toxicity. Methods of biological response monitoring might be helpful in achieving a favorable therapeutic ratio. PATIENT AND METHODS We report the case of a 77-year-old patient with squamous cell skin carcinoma originating within a pre...
The aim of this study was to investigate the relationship between standardized uptake value (SUV), obtained from [18F]fluorodeoxyglucose positron emission tomography (FDG PET), and treatment response and survival of inoperable NSCLC patients treated with high dose radiotherapy. Fifty-one patients were included, recording stage, performance, weight loss, tumour volume, histology, lymph node invo...
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