A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi-lipid vesicle. This composite system...

Silver, one of the precious and noble metals, is used in large quantities for many purposes, particularly in the photographic industry. It has been reported that 25% of the world’s silver needs are supplied by recycling and that 75% of this is obtained from photographic waste. For this reason, the methods applied to recover silver from photographic waste are important in reducing cost and time,...

The utilization and preparation of functional hybrid films for optical sensing applications and membranes is of utmost importance. In this work, we report the convenient and scalable preparation of self-crosslinking particle-based films derived by directed self-assembly of alkoxysilane-based cross-linkers as part of a core-shell particle architecture. The synthesis of well-designed monodisperse...

magnesium alloys in liquid-phase condition form surface oxide films due to their high rate of oxidation. oxide films enter the melt as a result of surface turbulence, and remain inside the workpiece after solidification. the incoherent nature of their interface causes decreases in mechanical properties and reliability of castings. the effect of critical velocity and greater velocities of enteri...

Atriblock copolymerof polystyrene-polybutadiene-polystyrene (KratonD1102)hasbeenused topattern barium titanate precursor with nanoscale modulations. The copolymer self-assembles to yield cylindrical polystyrene nanodomains in a polybutadiene matrix. The preorganized thin films of polymer are then selectively OH-functionalized in situ on the unsaturated carbon bonds in the polybutadiene matrix w...

Triptoreline is a potent agonist of luteinizing hormone-releasing hormone, currently used in the treatment of prostatic cancer where therapy may be required over months or years. Frequent injection of drug decreases patients’ compliance. The present study describes the formulation of a sustained release microparticulate drug delivery system containing triptoreline acetate, using poly (D,L lacti...

BACKGROUND For premature neonates needing parenteral nutrition (PN), a balanced lipid supply is crucial. The authors hypothesized that a lipid emulsion containing medium-chain triglycerides (MCTs) and soybean, olive, and fish oils would be as safe and well tolerated as a soybean emulsion while beneficially influencing the fatty acid profile. METHODS Double-blind, controlled study in 53 neonat...

Abstract A method was proposed for preparing multiple emulsions based on a double parallel-crank mechanism. The dispersed phase flows into the glass capillary, and capillary driven to make circular motion via connecting crank structure. Then, external shears through mechanism prepare water in oil (W/O) droplets, process of generation droplets simulated by CFD. effects rotating speed, diameter, ...

Colloidosomes are microcapsules whose shell consists of densely packed colloidal particles. Their physical properties such as permeability, mechanical strength, and biocompatibility can be precisely controlled through the proper choice of colloids and preparation conditions for their assembly. The high degree of control over their physical properties makes colloidosomes attractive structures fo...