We show that a sequence has effective Hausdorff dimension 1 if and only if it is coarsely similar to a Martin-Löf random sequence. More generally, a sequence has effective dimension s if and only if it is coarsely similar to a weakly s-random sequence. Further, for any s ă t, every sequence of effective dimension s can be changed on density at most H ́1ptq ́H ́1psq of its bits to produce a sequen...

Objective: To evaluate the frequency and association of p53 gene with increase histopathology categorizing “oral squamous cell carcinoma” patients. Study Design: Comparison Cross-sectional Research. Setting: Isra Dental College Hyderabad. Period: 1 November 2021 to 31 October 2022. Material & Methods: Sixty patients identified oral carcinomas were chosen by consecutive sampling from reporti...

QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation methods have been developed to help monitor pesticides in a range of food samples. These methods require many manual steps, such as shaking, centrifugation, and dispersive SPE cleanup, making it a quite labor-intensive process. There is a need for automating parts of QuEChERS extraction in order to improve laboratory ...

Molecularly targeted therapeutics have revolutionized the treatment of BRAFV600E-driven malignant melanoma, but rapid development resistance to BRAF kinase inhibitors (BRAFi) presents a significant obstacle. Here, we describe identification experimental melanoma overcoming NRAS-based BRAFi-resistance employing stringent genetic model BRAFi-resistance, i.e. isogenic cell lines that differ only b...