In Drosophila melanogaster and in Sciara ocellaris dosage compensation occurs by hypertranscription of the single male X chromosome. This article reports the cloning and characterization in S. ocellaris of the gene homologous to maleless (mle) of D. melanogaster, which implements dosage compensation. The Sciara mle gene produces a single transcript, encoding a helicase, which is present in both...

To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures seasonal occurring in parallel among Drosophila melanogaster populations. Specifically, estimated allele frequencies genome-wide from flies sampled early and late the growing season 20 widely dispersed We frequency shifts across North America Europe, demonstrating that is a general phe...

Abstract Drosophila melanogaster hemocytes are highly motile cells that crucial for successful embryogenesis and have important roles in the organism’s immunological response. Here we measure motion of using selective plane illumination microscopy. Every hemocyte cell one half an embryo is tracked during analysed a deep learning neural network. We show anomalous transport well described by frac...

Combretum micranthum leaves have been used traditionally in West Africa to manage pyrexia, cough, bronchitis, diabetes, malaria and other related ailments. It has also demonstrated alleviate high blood pressure skin inflammation. Drosophila melanogaster gaining acceptability biomedical research because of homologs its genes present humans the relative cost using flies. The purpose study is inve...

The Dobzhansky-Muller model posits that postzygotic reproductive isolation results from the evolution of incompatible epistatic interactions between species: alleles that function in the genetic background of one species can cause sterility or lethality in the genetic background of another species. Progress in identifying and characterizing factors involved in postzygotic isolation in Drosophil...

I present data on the evolution of intron lengths among 3 closely related Drosophila species, D. melanogaster, Drosophila simulans, and Drosophila yakuba. Using D. yakuba as an outgroup, I mapped insertion and deletion mutations in 148 introns (spanning approximately 30 kb) to the D. melanogaster and D. simulans lineages. Intron length evolution in the 2 sister species has been different: in D....

STAT92E is an essential transcription factor in Drosophila melanogaster for the development of several organs and the immune system. The JAK/STAT pathway employs different evolutionary conserved regulatory mechanisms to control biological processes. Numerous transcription factors in both mammals and invertebrates have been shown to be either activated or inhibited by a covalent modification wit...

Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in later stage of life. Those are termed as a neurotoxicant, which can be physical factor, toxin, an infection, radiation, or maybe drug. The incongruities caused due neurotoxicant further depend on toxicity compound. More importantly, neurotoxicity compound is concentration time point exposu...

W artykule przedstawiamy historię obserwacji i badań zegara biologicznego – począwszy od czasów Aleksandra Macedońskiego, gdy po raz pierwszy w literaturze znalazł się opis zjawiska cyklu dobowego, poprzez pierwsze badania naukowe wykorzystujące eksperymenty do charakterystyki rytmów u roślin, kończąc na dogłębnej analizie mechanizmu molekularnego owadów osiągnięcia, które uhonorowano najbardzi...

BackgroundCopper (Cu) and iron (Fe) are essential trace elements that when in excess capable of causing cytotoxic effects leading to lipid peroxidation promoting oxidative stress. Resveratrol (RES) is a natural polyphenol with antioxidant anti-inflammatory properties. This study was carried out evaluate the protective role RES Fe Cu sulphate-induced stress Drosophila melanogaster. MethodsAdult ...