fusion index in the management of renal transplants. J Nucl Med 1978; 19: 994. 8. Kerman RH, Floyd M, Conner W, et al. Combined immunologic and radionuc1eide techniques to monitor renal allograft rejection. Transplant Proc 1979; 11: 1229. 9. Kim EE, Pjura G, Lowry P, et al. CyclosPorin-A nephrotoxicity and acute cellular rejection in renal transplant recipients: correlation between radionucleid...

We present a patient with Fanconi syndrome who demonstrated poor renal uptake of 99mTc-DMSA and high urinary concentration of the tracer. A 99mTc-DTPA scan was normal and the creatinine clearance only minimally decreased. These findings suggest that 99mTc-DMSA may be accumulated in the kidney by glomerular filtration and subsequent tubular reabsorption, with the nonabsorbed fraction appearing i...

Liposomes entrapping gadolinium-DTPA (Gd-DTPA) were synthesized from 60 mole percent egg phosphatidylcholine (EPC) and 40 mole percent cholesterol or EPC alone entrapping Gd-DTPA in diameters of 100 and 200 nm. Rats bearing Morris hepatoma in their flanks were imaged by MR pre- and post-contrast with free Gd-DTPA and liposomal Gd-DTPA for up to four hours after IV contrast. Comparison of images...

UNLABELLED Antibodies accumulate nonspecifically in infectious foci due to the locally increased vascular permeability. This study describes a method of infection imaging in which 99mTc-DTPA (diethylenetriaminepentaacetic acid) is trapped at the target by a previously administered anti-DTPA monoclonal antibody. DTIn1. METHODS Rats with Staphylococcus aureus-infected calf muscle were injected ...

OBJECTIVE Understanding how best to measure renal function in HIV-infected patients is critical because estimated glomerular filtration rate (eGFR) in HIV-infected patients can be affected by ethnicity and body composition. We validated the available eGFR equations and compared them to the plasma Tc-diethylenetriaminepentaacetic acid (Tc-DTPA) clearance in HIV-infected patients. DESIGN Test o...

Introduction: Hydronephrosis is one of the major causes of referring infants for nuclear medicine investigation. Renal dynamic study is the most reliable investigation for such children. However direct evaluation of renogram leads to generation of parameters that have no physiological interpretation. The configuration of renogram is very much dependent upon the rate at which radiopharmace...

Technetium-99m-diethylene triamine pentaacetic acid ((99m)Tc-DTPA) has been widely used after (131)I-ortho-hippurate ((131)I-OIH) for renography and to test renal function. Only a few reports refer to normal values range of (99m)Tc-DTPA renography half maximum time (HMT). We have measured the normal value range of (99m)Tc-DTPA renography HMT in our department, of 433 healthy kidney donors fro...

UNLABELLED Receptor-targeted scintigraphy and radionuclide therapy with radiolabeled somatostatin analogs are successfully applied for somatostatin receptor-positive tumors. The synergistic effects of an apoptosis-inducing factor, for example, the Arg-Gly-Asp (RGD) motif, can increase the radiotherapeutic efficacy of these peptides. Hence, the tumoricidal effects of the hybrid peptide RGD-dieth...

Chromium is an element that possess several oxidation states and can easily pass from one to another, so its behavior in soils very complex. For this reason, determining fate the environment be difficult. In research work we tried determine which factors affect chromium fractionation natural soils, conditioning mobility. We paid special attention parent material. purpose, extraction experiments...