Since Aird, Bentall, Mehigan, and Roberts (1954) convincingly demonstrated a high incidence of blood group 0 in duodenal ulcer subjects there have been a number of confirmatory studies carried out in different ethnic groups and populations (McConnell, 1966). Studies have also been undertaken to see if there is an especially strong association between blood group 0 and some particular category o...

Anorectal Malformations are known to be associated with various other congenital anomalies including duodenal atresia. An association of congenital intrinsic duodenal obstruction causing partial duodenal obstruction in a patient with anorectal malformation is not described in literature. We describe a case of delayed presentation of congenital intrinsic duodenal obstruction in a child with high...

The proximal duodenal mucosa secretes HCO that serves to protect the epithelium from injury. In isolated human duodenal enterocytes in vitro, multiple luminal membrane proteins are involved in acid/base transport. We postulated that one or more isoforms of the Na(+)/H(+) exchanger (NHE) family is located on the apical surface of human duodenal mucosal epithelial cells and thereby contributes to...

BACKGROUND Primary distal renal tubular acidosis is a clinical disorder characterized by hyperchloremic metabolic acidosis, hypercalciuria, hypocitraturia, urinary acidification impairment, hypokalemia, metabolic bone disease, and nephrocalcinosis. Urinary acidification ability may be evaluated by an acidification test or maximum urinary pCO2 assessment with alkaline urine. The maximum urinary ...

Endocytic vesicles are acidified by an electrogenic proton pump and a parallel chloride conductance; however, acidification might be decreased if electrogenic transporters, such as Na,K-ATPase, that increase vesicle interior-positive membrane potential were also present. We examined this issue in early rat liver endosomes using ion substitution and inhibitors to alter Na,K-ATPase activity. Thes...

Ocean acidification has led to detectable changes in seawater chemistry around the world, which are associated with reduced growth and survival of many species. Acute ocean acidification “events” in the Pacific Northwest United States have jeopardized the $270 million, 3200 jobs/year shellfish aquaculture industry in Washington State, and this has contributed to the state’s broad-based, legisla...

purpose: to compare the prevalence of glaucoma among peptic ulcer patients with or without helicobacter pylori infection. methods: among 352 patients with an indication of gasterointestinal endoscopy for peptic problems, 120 patients in 18-88 years of age were included for evaluation of glaucoma. according to the results of histopathologic and urease test, they were divided into two groups: hel...

BACKGROUND Allergy and functional gastrointestinal disorders have been associated with eosinophilia in duodenal mucosa. AIM To assess the prevalence of eosinophilia in duodenal biopsies of patients attending for oesophogastroduodenoscopy and delineate associated clinical conditions. METHODS A total of 155 patients (mean age 55 years, 59% women) with normal duodenal biopsies were randomly se...

BACKGROUND Duodenal cancer is one of the leading causes of death in familial adenomatous polyposis (FAP) patients. An endoscopic surveillance programme was therefore initiated in 1988, the outcome of which is described in this paper. METHODS We report the 10 year follow up of 114 patients with FAP who were prospectively screened for the presence and severity of duodenal adenomas. RESULTS Si...