Duodenitis and gastric metaplasia, which is often colonised by Helicobacter pylori (H pylori), are increasingly recognised for their importance in the pathogenesis of duodenal ulcers. The situation is not clear in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs), who have a higher risk of peptic ulceration. The aim of this study was to identify the duodenal histological abnorma...

Gastric (foveolar) metaplasia (GM) in the duodenum occurs many cases where duodenitis develops histologically. However, few studies have investigated presence of GM celiac patients. This study aimed to determine prevalence and its relationship with clinicopathological parameters untreated pediatric Duodenal biopsy specimens 153 were analyzed. MUC5AC immunohistochemical staining was applied all ...

Although the detection rate and treatment opportunities regarding superficial duodenal epithelial tumors (SDET) are improving, an algorithm for a diagnosis based on magnified endoscopic examination with image-enhanced endoscopy (IEE-ME) has not yet been established. We focused possibility that surface structure of SDET differs depending mucin phenotypes. Hence, structure, we developed to differ...

tumors that account for 2 % to 13.6 % of all gastrointestinal carcinoids, and no guidelines are available for their treat− ment. Small (< 2 cm) nonperiampullary duodenal carcinoids without submucosal invasion have been termed early stage duodenal carcinoids (esDC) [1]; their clinical course appears favorable and en− doscopic treatment would seem to be a feasible treatment option. We report on a...

Over the past decade, PCR-based methodologies have been introduced to complement or even replace histopathologic study of biopsy specimens for the diagnosis of Whipple’s disease (12). However, positive PCR results have been reported on testing small-bowel and saliva specimens from asymptomatic patients (3, 4, 11). Although these results have not been independently confirmed (8), they have nonet...

Figure 2. Magnified endoscopic view of the white granule around the duodenal papila, which was suggestive of a su bepithelial or submucosal lesion with local interruption of lymphatic flow. Figure 3. Histological picture of biopsy specimen showing that smal cleaved lymphoid cels with some large cels of the centroblastic type were infiltrated into the lamina propria of duodenum. □ PICTURES IN CL...

We report an unusual case of Whipple's disease diagnosed with help from the patient himself. The patient presented with rash resembling dermatitis herpetiformis, constipation, and intermittent diarrhea. A suspicion of celiac disease led to duodenal biopsy, which showed features of Whipple's disease on histology and electron microscopy.

The present study is a unique illustration of duodenal amyloidosis initially manifesting with iron deficiency anemia. It underscores the importance of clinical suspicion of amyloidosis while performing upper gastrointestinal endoscopy with a biopsy to establish the definite diagnosis in patients with unexplained iron deficiency anemia.

A 65 year-old male was admitted to the University hospital with obstructive jaundice. Endoscopic examination revealed a grossly abnormal major ampulla, situated at the edge of a large duodenal diverticulum. Biopsy of the ampulla was positive for villous adenoma. We describe the technique utilized to successfully perform an end-bloc endoscopic resection of a major ampulla on a diverticulum.

Background & Aims: Celiac disease or gluten-sensitive enteropathy is a relatively uncommon digestive disease. Moreover, irritable bowel syndrome (IBS) is a common functional bowel disorder. Some IBS patients have celiac disease, with similar IBS symptoms in addition to some serious complications. The only possible treatment for this condition is changing the patients diet (gluten free diet). Gi...