BACKGROUND AND OBJECTIVE To date, many different materials have been proposed for root canal fillings, but gutta-percha (used with various types of sealers) has remained the material of choice for over a century. A new root canal obturation system, the Epiphany endodontic obturation system, has been developed to replace gutta-percha and traditional sealers for root canal obturation. The purpose...

Dystrophin deficiency leads to increased proteasome activity in skeletal muscle. Previous observations suggest short-term inhibition of the proteasome restores dystrophin expression. Contrary to our hypothesis, eight days of MG-132 administration to mdx mice increased susceptibility to contraction induced injury and Evan’s blue dye penetration compared to controls. Following six weeks of MG-132...

Materials and Methods: Class V cavities were prepared on 20 extracted mandibular molars. The cavities in the experimental groups were pre-treated with a scrub of cavity disinfectants followed by application of bonding agent. Preparations without cavity disinfectants served as control. After the cavities were restored with resin composite (G-Aenial Universal Flo), the specimens were subjected to...

introduction: favorable apical seal of root filling materials is a crucial factor for a successful root canal treatment. the aim of this in vitro study was to compare bacterial and dye microleakage of two root canal filling materials including standard gutta-percha and nanosilver coated gutta-percha, and to evaluate the agreement between results of these two methods . materials & methods: fifty...

introduction: the provision of an effective apical seal is an essential factor when choosing an appropriate material for success of root-end surgeries. root-end resection, preparation and obturation should provide an adequate apical seal. the aim of this in vitro study was to investigate bacterial and dye microleakage of four different root-end filling materials and compare the efficacy of thes...

Dystrophin deficiency leads to increased proteasome activity in skeletal muscle. Previous observations suggest short-term inhibition of the proteasome restores dystrophin expression. Contrary to our hypothesis, eight days of MG-132 administration to mdx mice increased susceptibility to contraction induced injury and Evan's blue dye penetration compared to controls. Following six weeks of MG-132...

A glass electrode apparatus is described with which pH measurements can be made with as small volumes as 2 drops (about 0.14 cc.) of solution. Using this apparatus the change of pH of the vacuolar sap of Nitella, due to the penetration of brilliant cresyl blue, has been readily followed. The sap and the dye have been found to poison the usual type of hydrogen electrode.

INTRODUCTION The aim of this study was to compare the effect of the EndoVac irrigation system (SybronEndo, Orange, CA) and conventional endodontic needle irrigation on sealer penetration into dentinal tubules. METHODS Forty single-rooted, recently extracted human maxillary central incisors were randomly divided into 2 groups according to the irrigation technique used: conventional endodontic ...

Recently, ultrasound (US)-based drug delivery strategies have received attention to improve enhanced permeation and retention (EPR) effect-based passive targeting efficiency of nanoparticles in vitro and in vivo conditions. Among the US treatment techniques, pulsed-high intensity focused ultrasound (pHIFU) have specialized for improving tissue penetration of various macromolecules and nanoparti...

Transient chlorine concentration profiles were measured in biofilms during disinfection by use of a microelectrode developed for this investigation. The electrode had a tip diameter of ca. 10 microm and was sensitive to chlorine in the micromolar range. The biofilms contained Pseudomonas aeruginosa and Klebsiella pneumoniae. Chlorine concentrations measured in biofilms were typically only 20% o...