PURPOSE To evaluate the effects of the alpha(2)-adrenergic agonists (clonidine, apraclonidine, and guanfacine) on lipopolysaccharide (LPS)-induced aqueous flare elevation in pigmented rabbits. METHODS Anterior uveitis was induced with an intravenous injection of LPS (0.5 microg/kg) in an ear vein. The reproducibility of experimental uveitis induced by LPS (0.5 microg/kg) was also determined. ...

Based on short recordings, the rectum has been shown to have contractions with a frequency of five to 10 cycles per minute and slow contractions at three cycles per minute. To define anorectal motility over a prolonged period of time, we have studied 12 healthy volunteers using a fine pressure sensitive anorectal probe. A total of 240 hours of recording was obtained. We observed three types of ...

OBJECTIVE The aim of this study was to compare protective effects of ischemic and potential protective effects of pharmacological preconditioning with omeprazole on isolated rat heart subjected to ischemia/reperfusion. METHODS The hearts of male Wistar albino rats were excised and perfused on a Langendorff apparatus. In control group (CG) after stabilization period, hearts were subjected to g...

The dose response of duodenal bicarbonate production during synthetic porcine secretin infusions was studied in six healthy volunteers and related to plasma secretin immunoreactivity. Secretin was infused in each individual at four different doses from 0-1 to 2-7 CU/kg/h, each infusion lasting for 60 minutes. Mean maximal bicarbonate secretion was 33 +/- 4 mEq/h. The secretin plasma level for h...

INTRODUCTION Ischemic postconditioning has been recognized as effective in the prevention of reperfusion injury in situations of ischemia and reperfusion in various organs and tissues. However, it remains unclear what would be the best way to accomplish it, since studies show great variation in the method of their application. OBJECTIVE To assess the protective effect of ischemic postconditio...

objectives:this study used a quasi-experimental method inthe pretest-posttest to evaluate the efficacy of cognitive-existential group therapy on hopefulness in parents of children with cancer. methods:thirty parents (24 to 54 years old) of children with cancer were divided randomly into experimental and control groups. both groups were assessed with miller hope scale (1988), as pre-test. the ex...

Abstract Introduction During the COVID-19 pandemic, Major Trauma services were subject to significant challenges including reduced access Computed Tomography (CT) scanning and restrictions on operative intervention due limited intensive care beds. This study evaluated pandemic’s impact timeliness of imaging surgical intervention. Method observational compared 2 cohorts patients admitted in a 10...

Infectious Bursal Disease (IBD) has been reported in Indonesia since 1983 and become an endemic disease. IBD virus is known to be quite resistant physical chemical reagents compared other viruses, causing this disease hard eradicated. This study aims evaluate the effect of heat disinfectants on viability virus. was conducted using a local isolate IBDV obtained from IRCVS. The exposed disinfecta...

Abstract Introduction The sleep-related withdrawal of noradrenergic excitation and increased cholinergic inhibition hypoglossal motoneurons (HM), which control the tone GG, largest protruder muscle tongue, play a critical role in obstructive sleep apnea pathophysiology. In an animal model REM sleep, antagonism alpha1 signaling by microinjections prazosin into nucleus (HN) strongly decreased ner...

Objective: The present research aimed to assess the effectiveness of Acceptance and Commitment Therapy (ACT) on the hope of patients with breast cancer undergoing chemotherapy. Methods: In this quasi-experimental study, 30 patients with breast cancer were selected by convenience sampling method and randomly assigned to experimental and control groups. The experimental group attended ACT sessio...