AIMS Two tablet formulations of buprenorphine (a buprenorphine mono-product, Subutex, and a buprenorphine/naloxone combination product, Suboxone) are available for use in the treatment of opioid addiction; however, the bulk of the clinical studies supporting its approval by the US Food and Drug Administration (FDA) were conducted with a sublingual liquid preparation. To assist the clinician in ...

BACKGROUND Local slow release implant provided long term and stable drug release in the lesion. The objective of this study was to fabricate biodegradable slow release INH/PLLA tablet via 3 dimensional printing technique (3DP) and to compare the drug release characteristics of three different structured tablets in vitro. METHODS Three different drug delivery systems (columnar-shaped tablet (C...

Abstract This paper argues for the interpretation of words on Basel BS 415 as markers not only song’s content, but equally its musical notation. Predating such notation, inscribed syllables reflect language’s priority over music, opposed to later reversal these priorities. On 415, written words’ orthography sufficed an indication syllables’ prosodic qualities that enabled accompaniment follow l...

in expecting much from their joint labours. The work before us is divided into two portions, the first embracing the history, classification, statistics of insanity, is from the pen of Dr. Tuke; the remaining chapters, which treat of the diagnosis, pathology, and treatment of mental disorders, are by Dr. Bucknill. Our space will not allow us to do more than briefly refer to some of the more imp...

As the only available sweetener honey was an important food for Homo sapiens since his very beginnings. Indeed, the relation between bees and Homo sapiens started as early as stone age . In order to reach the sweet honey, man was ready to risk his life (Figure 1). Already the first written reference to honey, a Sumerian tablet writing, dating back to 2100-2000 BC, mentions honey’s use as a drug...

Electronic screens on laptop and tablet computers are being used for reading text, often while multitasking. Two experimental studies with college students explored the effect of medium and opportunities to multitask on reading (Study 1) and report writing (Study 2). In study 1, participants (N = 120) read an easy and difficult passage on paper, a laptop, or tablet, while either multitasking or...

Tablets and mobile devices are used in various situations in everyday life. Several researchers have reported the effectiveness of tilting a tablet in enabling a high degree of usability. Tablets are also increasingly popular in elementary school classrooms. The use of tablets in schools is considered to be different from their common use in daily life because students have many opportunities t...

This research addresses the change in how the Spanish University Entrance Examination can be delivered in the future. There is a wide acknowledgement that computer tests are very demanding for the delivering institutions which makes computer language testing difficult to implement. However, the use of tablet PCs can facilitate the delivery at even lower cost than the regular computer based lang...