نتایج جستجو برای: eb1

تعداد نتایج: 597  

Journal: :Biochemical Society Transactions 2009

2015

Lindberg SW1*, Agner T2 and Pedersen EB1 1Department of Occupational and Environmental Medicine, University of Copenhagen, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark 2Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark *Corresponding author: Sara Lindberg, Department of Occupational and Environmental Medicine, Bispebjerg Hospital, Denmark,...

Journal: :Cardiovascular research 2014
Esperanza Agullo-Pascual Xianming Lin Alejandra Leo-Macias Mingliang Zhang Feng-Xia Liang Zhen Li Anna Pfenniger Indra Lübkemeier Sarah Keegan David Fenyö Klaus Willecke Eli Rothenberg Mario Delmar

AIMS It is well known that connexin43 (Cx43) forms gap junctions. We recently showed that Cx43 is also part of a protein-interacting network that regulates excitability. Cardiac-specific truncation of Cx43 C-terminus (mutant 'Cx43D378stop') led to lethal arrhythmias. Cx43D378stop localized to the intercalated disc (ID); cell-cell coupling was normal, but there was significant sodium current (IN...

2017
Yuzy Matsuo Sebastian P. Maurer Thomas Surrey Takashi Toda

The Ndc80 complex is a conserved outer kinetochore protein complex consisting of Ndc80 (Hec1), Nuf2, Spc24 and Spc25. This complex comprises a major, if not the sole, platform with which the plus ends of the spindle microtubules directly interact. In fission yeast, several studies indicate that multiple microtubule-associated proteins including the Dis1/chTOG microtubule polymerase and the Mal3...

Journal: :Current Biology 2003
Elizabeth E. Grevengoed Mark Peifer

Cell and tissue integrity requires the coordination of actin and microtubules and the linkage of these cytoskeletal elements to cell junctions. New findings reveal that the cytoskeletal linker protein Short stop works with EB1 and APC1 to help carry out this function.

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