INTRODUCTION Wellens' syndrome, also called left anterior descending (LAD) coronary T-wave syndrome, is a characteristic electrocardiographic (ECG) pattern suggestive of coronary artery disease in the preinfarction stage. [1–3] ECG changes in Wellens' syndrome may signify critical stenosis in the proximal LAD coronary artery. [1–5] Furthermore, ECG changes may occur during a pain-free period wi...

The aim of this study was to define the electrocardiogram (ECG) changes following the moderate to severe CO intoxication in rats, and also evaluating the effect of erythropoietin (EPO) on observed cardiac disturbances. The growing literature on erythropoietin effect on cardiac ischemia led us to question its effect on cardiotoxicity due to the carbon monoxide poisoning. Wistar rats were exposed...

In order to search into the underlying mechanisms of ECG changes suggestive of ischemia observed in humans and in rabbits after administration of 5-fluorouracil (5-FU), experiments were performed in anesthetized open-chest guinea pigs. The substance produced similar ECG changes in this species as well, after a rather long latent period of around 3 hours after intravenous administration. The inc...

BACKGROUND ECG changes, similar to those seen during myocardial ischaemia, together with symptoms of chest pain, are common during Caesarean section (CS). We hypothesized that oxytocin administration has cardiovascular effects leading to these symptoms and ECG changes. METHODS Forty women undergoing elective CS under spinal anaesthesia were given an i.v. bolus of either 10 IU of oxytocin (Gro...