Seizures have both local and remote effects on nervous system function. Whereas propagated seizures are known to disrupt cerebral activity, little work has been done on remote network effects of seizures that do not propagate. Human focal temporal lobe seizures demonstrate remote changes including slow waves on electroencephalography (EEG) and decreased cerebral blood flow (CBF) in the neocorte...

We introduce an anatomical and electrophysiological model of deep brain structures dedicated to magnetoencephalography (MEG) and electroencephalography (EEG) source imaging. So far, most imaging inverse models considered that MEG/EEG surface signals were predominantly produced by cortical, hence superficial, neural currents. Here we question whether crucial deep brain structures such as the bas...

Acute and Chronic Effects of Unilateral Cerebral Infarction on the EEG and Behavior of the Rat • Anoxic ischemia with resultant unilateral cerebral infarction was produced in the rat by unilateral ligation of the external and common carotid arteries and exposure of the animal to nitrogen. EEG and behavior were studied for one month after the anoxic insult. Infarcted animals showed prominent cir...

BACKGROUND It would be useful to have an open-source electroencephalographic (EEG) index of gamma-amino-butyric acid (GABA)-ergic anaesthetic drug effect that is resistant to eye-blink artifact, responds rapidly to changes in EEG pattern, and can be linked to underlying neurophysiological and neuropharmacological mechanisms that control the conscious state. METHODS The EEG waveform can be des...

In this paper, we present our strategy for sonification of EEG signals as part of the ‘listening to the mind listening’ project [1]. It is generally thought that similarities between EEG signals recorded at two distinct points on the scalp indicate that the brain is performing the same task at these two points. A high correlation coefficient can be used as an indicator of such similarities. Usi...

OBJECTIVE To determine whether the absence of early epileptiform abnormalities predicts absence of later seizures on continuous EEG monitoring of hospitalized patients. METHODS We retrospectively reviewed 242 consecutive patients without a prior generalized convulsive seizure or active epilepsy who underwent continuous EEG monitoring lasting at least 18 hours for detection of nonconvulsive se...

Spikes and sharp waves recorded on scalp EEG may play an important role in identifying the epileptogenic network as well as in understanding the central nervous system. Therefore, several automatic and semi-automatic methods have been implemented to detect these two neural transients. A consistent gold standard associated with a high degree of agreement among neuroscientists is required to meas...

Based on electroencephalographic recordings (EEG), the human sleep/wake cycle has been subdivided in 4 major stages. The passage from wakefulness to light (lSWS) and deep (dSWS) slow wave sleep (SWS) is characterized by a progressive slowing of the EEG, more or less associated with transient elements (spindle; K complex), while the 4th vigilance stage (rapid eye movements or paradoxical sleep P...

Ictal epileptiform discharges (EDs) are characteristic signal patterns of scalp electroencephalogram (EEG) or intracranial EEG (iEEG) recorded from patients with epilepsy, which assist with the diagnosis and characterization of various types of epilepsy. The EEG signal, however, is often recorded from patients with epilepsy for a long period of time, and thus detection and identification of EDs...

We analyze the respective roles of neuro-imaging and EEG in the assessment of 11 children with holoprosencephaly and epilepsy. Seizures were present in seven patients (64%); six were treated with antiepileptic drugs; five had intractable epilepsy. Two of the patients with intractable epilepsy became seizure-free under polytherapy. Fourteen EEG recordings were performed in eight patients. The ab...