Type 2 diabetes is characterized by increased insulin resistance and impaired insulin secretion. Type 2 diabetes is also associated with low-grade inflammation and increased levels of proinflammatory cytokines such as TNF-α. TNF-α has been shown to impair peripheral insulin signaling in vitro and in vivo. However, it is unclear whether TNF-α may also affect endogenous glucose production (EGP) d...

Background: Growth hormone (GH) is known to affect insulin and glucose metabolism.  Blocking its effects in acromegalic patients improves diabetes and glucose metabolism. We aimed to determine the effect of pegvisomant, a GH receptor antagonist, on insulin resistance, endogenous glucose production (EGP) and lipolysis in insulin resistant non-diabetic men.  Methods: Four men between the ages of ...

In the present study the hypothesis tested was that prior exercise may blunt counterregulatory responses to subsequent hypoglycemia. Healthy subjects [15 females (f)/15 males (m), age 27 +/- 1 yr, body mass index 22 +/- 1 kg/m(2), hemoglobin A(Ic) 5.6 +/- 0.5%] were studied during 2-day experiments. Day 1 involved either 90-min morning and afternoon cycle exercise at 50% maximal O2 uptake (VO2(...

EGP and IGP are the key components of the present internet infrastructure. Routers in a domain forward IP packet within and between domains. Each domain uses an intra-domain routing protocol known as Interior Gateway Protocol (IGP) like IS-IS, OSPF, RIP etc to populate the routing tables of its routers. Routing information must also be exchanged between domains to ensure that a host in one doma...

Job shop scheduling (JSS) problems are optimisation problems that have been studied extensively due to their computational complexity and application in manufacturing systems. This paper focuses on a dynamic JSS problem to minimise the total weighted tardiness. In dynamic JSS, jobs’ attributes are only revealed after they arrive at the shop floor. Dispatching rule heuristics are prominent appro...

In project scheduling studies, to the best of our knowledge, hyper-heuristic collaborative is first-time applied with random activity durations. A based ensemble genetic programming (HH-EGP) method proposed for solving stochastic resource constrained problem (SRCPSP) by evolving an priority rules (PRs). The approach features (1) integrating critical path into resource-based policy class generat...

In social stratification research, the most frequently used class schema are based on employment relations (EGP and ESEC). These schemes have been propelled to paradigms for research mobility educational inequalities applied in cross-national both genders. Using European Working Conditions Survey, we examine their criterion construct validity across 31 countries We investigate whether classes w...

This study was conducted to test the hypothesis of the activation of glucose-6-phosphatase (G-6-Pase) in situations where the liver is supposed to sustain high glucose supply, such as during the counterregulatory response to hypoglycemia. Hypoglycemia was induced by insulin infusion in anesthetized rats. Despite hyperinsulinemia, endogenous glucose production (EGP), assessed by [3-(3)H]glucose ...

ESP classes are usually designed for college students after they finish EGP learning. Accordingly, textbooks used use the ones. Logically, should be lexically more sophisticated than ones, because linguistic contents also important concerns teaching, and promote students’ language development in addition to their professional advancement. This research aims compare lexical complexity between am...