Nuclear motions like rotation, translation and deformation suggest that the nucleus is acted upon by mechanical forces. Molecular linkages with the cytoskeleton are thought to transfer forces to the nuclear surface. We developed an approach to apply reproducible, known mechanical forces to the nucleus in spread adherent cells and quantified the elastic response of the mechanically integrated nu...

In this study, the distribution patterns of neural crest (NC) cells (NCCs) in the developing vascular system of the chick were thoroughly studied and examined for a correlation with smooth muscle cell differentiation and vascular morphogenesis. For this purpose, we performed long-term lineage tracing using quail-chick chimera techniques and premigratory NCC infection with a replication-incompet...

In recent years, the Lamb wave analysis by the multi-channel analysis of surface waves (MASW) for concrete structures has been an effective nondestructive evaluation, such as the condition assessment and dimension identification by the elastic wave velocities and their reflections from boundaries. This study proposes an effective Lamb wave analysis by the practical application of MASW to concre...

In this study, the distribution patterns of neural crest (NC) cells (NCCs) in the developing vascular system of the chick were thoroughly studied and examined for a correlation with smooth muscle cell differentiation and vascular morphogenesis. For this purpose, we performed long-term lineage tracing using quail-chick chimera techniques and premigratory NCC infection with a replication-incompet...

Manipulation of interstitial fluid pressure (IFP) has a clinical potential when used in conjunction with near-infrared spectroscopy for the detection of breast cancer. In order to better interpret how the applied pressure alters the vascular space and interstitial water volumes in breast tissue, a study on tissue-mimicking, gelatin phantoms was carried out to mimic the translation of external f...

Based on the analytical solution of Crouch to the problem of a constant discontinuity in displacement over a finite line segment in an infinite elastic solid, in the present paper, the crack-tip displacement discontinuity elements, which can be classified as the left and the right crack-tip elements, are presented to model the singularity of stress near a crack tip. Furthermore, the crack-tip e...

Given an image of an atomic crystal, we propose a variational method which at each image location determines the local crystal state and which localizes and characterizes crystal defects. In particular, the local crystal orientation and elastic distortion are detected, as well as dislocations, and grain and twin boundaries. To this end an energy functional is devised whose minimization yields a...

A general method for fluid solid interaction problem simulations has been developed in 3D algorithm using incompressible smoothed particle hydrodynamics (SPH) method. The solid is assumed to be rigid so it can be considered as moving boundaries for fluid. Using repulsive force has been proved to be an efficient boundary treatment for incompressible SPH method before with 2D examples. The advant...

We employ classical molecular dynamics to calculate elastic properties and to model the nucleation and propagation of deformation twins in calcite, both as a pure crystal and with magnesium and aspartate inclusions. The twinning is induced by applying uniaxial strain to the crystal and relaxing all stress components except the uniaxial component. A detailed analysis of the atomistic processes r...