Sir, Down’s syndrome (trisomy 21) is a multisystem disorder with a birth incidence of approximately 1 in 700 live births, making it the most common autosomal chromosomal disorder causing mental retardation. Down’s Syndrome is also associated with an increased incidence of cutaneous disorders.[1-4] In particular, there seems to be an increased incidence of xerosis, atopic dermatitis, seborrheic ...

Severe pulmonary or aortic valve stenosis may be lethal to the neonate if untreated. Two patients suffering from pulmonary stenosis and four with aortic stenosis were relieved surgically with the use of full cardiopulmonary bypass. Both neonates with pulmonary stenosis did well, making them the youngest recorded survivors of such treatment. Two of the four patients with aortic stenosis have don...

Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...

INTRODUCTION Skin photoaging is the consequence of solar UV exposure, and DNA damage is an important part of this process. The objective of the current work was to demonstrate that in vitro skin models can be utilized to confirm that DNA damage protection is provided by sunscreens. METHODS Skin equivalents were exposed to full-spectrum UV light administered with a standard research solar simu...

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