Recent advances in label free DNA hybridization sensors employing electrochemical impedance spectroscopy (EIS) as a detection tool are reviewed. These sensors are based on the modulation of the blocking ability of an electrode modified with a probe DNA by an analyte, i.e., target DNA. The probe DNA is immobilized on a self-assembled monolayer, a conducting polymer film, or a layer of nanostruct...

In this paper, a fine gold nanostructure synthesized on selective planar microelectrodes in micro-chip is realized by using an advanced hybrid fabrication approach incorporating growth of nanorods (NRs) with gold electroplating. By this developed nanostructure, integration of in-situ surface-enhanced Raman spectroscopy (SERS) detection with electrochemical impedance spectroscopy (EIS) measureme...

A rapid and simple method for quantitative monitoring of Brucella melitensis using electrochemical impedance spectroscopy (EIS) is reported for the first time. The label-free immunosensors were fabricated by immobilizing Brucella melitensis antibody on the surface of gold nanoparticle-modified screen-printed carbon electrodes (GNP-SPCEs). Cyclic voltammetry (CV) and EIS were used to characteriz...

Porous electrodes provide high-surface-area supports for the catalysts of many reactions, but the influences of electrode preparation conditions on electrocatalysts are not always well understood. Electrochemical impedance spectroscopy ~EIS! can provide extensive information about an electrode, but the models describing the spectra are often too idealized to draw useful conclusions. We describe...

A simple, selective and sensitive electrochemical method is described for the determination of different aldehydes at glassy carbon electrode using electrochemical impedance spectroscopy (EIS). The measurements were performed after their derivatization with 2,4-dinitrophenylhydrazine (DNPH) in acidic medium. The impedance measurements were investigated in the frequency range from 100 mHz to 100...

Self-assembled multilayer films of hyaluronic acid (HA) and the protein myoglobin (Mb) were built up layer by layer on Au covered quartz crystal microbalance (AuQCM) electrode substrates. Film formation and growth were monitored by an electrochemical quartz crystal microbalance (EQCM), and the step-by-step construction was investigated through quantification of the mass variation corresponding ...

We report on the fabrication and electrochemical impedance characterization of a parallel plate capacitance sensor for ocean water salinity monitoring. The standard printed circuit board PCB fabricated and assembled sensor shows excellent response to changes in salinity with a sensitivity of 3.3 k /PSU. Use of the standard PCB process, necessitated by the requirement of low cost and ease of fab...

Electrochemical impedance spectroscopy (EIS) is a unique non-destructive technique employed to analyze various devices in different energy storage applications. It characterizes materials and interfaces for their properties heterogeneous systems employing equivalent circuits as models. So far, it has been used the performance of photovoltaic cells, fuel batteries, other devices, through circuit...

In this work, we have systematically investigated the formation and characterization of Self-assembled Monolayer (SAM) films of several silanes on indium tin oxide (ITO) surfaces. Silane molecules having different domains namely substrate binding domain (siloxanes), electron transport region (aliphatic and aromatic spacer) and terminal functional groups (-SH, -CH(3) groups) are employed for the...

Electrochemical behaviors of 1-naphthaleneacetic acid (NAA) at an ionic liquid N-butylpyridinium hexafluorophosphate (BPPF6/CPE) modified carbon paste electrode was investigated by cyclic voltammetry (CV) and further used for NAA sample determination. The experimental results showed that NAA at both the bared and the modified electrode showed an irreversible oxidation process, but at the modifi...