We performed a meta-analysis of randomised clinical studies in which the efficacy and toxicity of the same total daily dose of aminoglycosides administered once-daily was compared with multiple divided daily dosing for treating human infections. Of twenty-eight publications identified from a literature search using Medline 19 publications of 20 study comparisons involving 2881 patients met the ...

We report a rare case of benign paroxysmal vertigo (BPV) of childhood transitioning into basilar migraine (BM) that was effectively treated with lomerizine. A 6-year-old male visited our hospital complaining of repeated attacks of vertigo for 3 months. The patient's vertigo attacks lasted for several hours and were accompanied by nausea, vomiting, intense fear and loss of consciousness. No nyst...

OBJECTIVES/HYPOTHESIS Periodic alternating nystagmus (PAN) is most commonly found either in its congenital form or after cerebellar/pontomedullary lesions. However, we identified PAN in 10 patients with peripheral vestibular disorders and will try to describe their characteristics to aid in the differential diagnosis between peripheral and central etiologies. STUDY DESIGN Observation of a cas...

OBJECTIVE To propose an etiology for a syndrome of bilateral vestibular hypofunction and sound and/or pressure-evoked eye movements with normal hearing thresholds. DESIGN Retrospective case series. SETTING Tertiary care referral center. PATIENTS Four patients with bilateral vestibular hypofunction, sound and/or pressure-evoked nystagmus and normal hearing thresholds were identified over a...

BACKGROUND No studies to date have attempted to evaluate frontotemporal lobar degeneration from the perspective of the vestibular system. OBJECTIVE The present study examined vestibular function in patients with frontotemporal dementia (FTD) clinical syndrome and evaluated whether vestibular disorders are involved in the clinical symptoms due to FTD. METHODS Fourteen patients with FTD syndr...

While vestibulo-oculomotor and vestibulo-spinal functions are usually investigated by means of electronystagmography and stabilometry, environmental exploration and navigation cannot be easily studied in the laboratory. We propose that virtual reality (VR) can provide a solution, especially for those interested in the assessment of vestibular influence over spatial cognitive activities. Subject...

A significant number of patients of all age groups are seen in Otorhinolaryngology having symptoms of vertigo. Further due to automobile accidents and changing life style pattern there is constant increase in the patients presenting with dizziness and imbalance at early age. This retrospective study was undertaken to study the prevalence of vertigo in different age groups, male and female ratio...

..................................................................................................................... 9 REVIEW OF THE LITERATURE .............................................................................. 10 1. CLINICAL CHARACTERISTICS OF MIGRAINE AND EPISODIC ATAXIA TYPE 2 ........................... 10 1.1. Migraine with and without aura .......................................

OBJECTIVES We examined the association between the size and cross-sectional area of the superior vestibular nerve as measured on constructive interference in steady-state (CISS) parasagittal magnetic resonance imaging (MRI) and the vestibular nerve function as measured by electronystagmography. METHODS The retrospective observational cohort study took place at an academic tertiary referral ce...

mainder is concerned with the vestibular system. This book will be of greatest value to clinical and laboratory investigators studying postural control or vestibular function. The twenty-six members of the symposium are prominent investigators from such fields as neuroanatomy, neurophysiology, and otolaryngology. The material is based upon published results which appeared up to late 1967. There...