Extensive retinal vascular disease was noted in three patients from two families with Favre-Goldmann syndrome. In addition to classical features they had pronounced leakage from some retinal vessels. Vessels were either opaque ('sclerotic') or non-perfused. Cystoid macular oedema was a contributing cause of decreased vision. Two of the three patients showed a discrepancy on electroretinography ...

Multifocal electroretinography (mfERG) is a valuable technique in assessing macular function in retinal disease objectively as it provides spatial information. Altered responses give an estimate of the extent of central retinal dysfunction. Fixation is known to be an important technical factor in mfERG recording. We present findings in a patient with asymptomatic intermittent exotropia that rei...

Multifocal electroretinography (mfERG) is a valuable technique in assessing macular function in retinal disease objectively as it provides spatial information. Altered responses give an estimate of the extent of central retinal dysfunction. Fixation is known to be an important technical factor in mfERG recording. We present findings in a patient with asymptomatic intermittent exotropia that rei...

Submit Manuscript | http://medcraveonline.com the disease, central vision is normally preserved. When macula starts to become affected this can lead to central visual loss [1]. Normally patients present with night blindness and restricted peripheral visual field [2]. Examination of the retina shows arteriolar attenuation, bony spicules and pigmentary changes affecting the mid retinal periphery ...

The early receptor potential (ERP) of the retina was found by BROWN and MURAKAMI (1964a, b) in the monkey. The ERP has been reported to exist in some other animals and to be closely linked with the initial events of visual excitation (CONE, 1964, 1965; PAK and CONE, 1964; PAK and EBREY, 1965; BROWN, 1965; BROWN, WATANABE and MURAKAMI, 1965; PAK, 1965; ARDEN and IKEDA, 1965, 1966; BRINDLEY and G...

A case of traumatic complete avulsion of the optic nerve is reported together with fluorescein angiography and electrodiagnostic findings. Despite the disappearance of the central vessels, circulation remained in the branch retinal vessels and angiography demonstrated communication between peripapillary choroidal vessels and the superior temporal artery. The visually-evoked cortical response wa...

P ETERSEN-JONES AND COLLEAGUES PERformed an important proof-of-principle study titled “Improvement of Visual Performance With Intravitreal Administration of 9-cisRetinal in Rpe65-Mutant Dogs,” published in this issue of the Archives. As a component of comprehensive preclinical studies, its primary goal was to determine the efficacy of 9-cis-retinal in restoring visual function assessed by both ...

PURPOSE To examine the S-cone ERG in subjects with and without L and M-cone function. METHODS Ganzfeld spectral flashes in the presence of strong Ganzfeld adapting fields are used to elicit S-cone ERGs. RESULTS The S-cone ERG b-wave ranges from 0.2 to 4 mV in amplitude and 38-45 msec in implicit time. There is a progressive decrease in amplitude with age. The response is similar in subjects...