Stem cells based tissue engineering requires biocompatible materials, which allow the cells to adhere, expand, and differentiate in a large scale. An ideal biomaterial for clinical application should be free from mammalian products which cause immune reactivities and pathogen infections. We invented a novel biodegradable poly(L-lactic-co-ε-caprolactone)-sericin (PLCL-SC) copolymer membrane whic...

BACKGROUND The purpose of this study was to develop novel sandwich-structured nanofibrous membranes to provide sustained-release delivery of vancomycin, gentamicin, and lidocaine for repair of infected wounds. METHODS To prepare the biodegradable membranes, poly(D, L)-lactide-co-glycolide (PLGA), collagen, and various pharmaceuticals, including vancomycin, gentamicin, and lidocaine, were firs...

Particulate matter (PM) pollution has become a serious threat to human health. Accordingly, an air filtration media that can efficiently remove particulate should be developed immediately. Nanofibrous membrane filter prepared by electrospinning technology nanoscale diameter, high specific surface area, and relatively porosity, which are suitable for dust removal. This paper explored the effects...

This study concentrates on the development of biodegradable nanofiber membranes with controlled drug release to ensure reduced tissue adhesion and accelerated healing. Nanofibers of poly(lactic-co-glycolic acid) (PLGA) loaded with epigallocatechin-3-O-gallate (EGCG), the most bioactive polyphenolic compound in green tea, were electrospun. The physicochemical and biomechanical properties of EGCG...

Guided bone regeneration involves excluding non-osteogenic cells from the surrounding soft tissues and allowing osteogenic originating native to inhabit defect. The aim of this work was fabricate, analyze antibiofilm activity evaluate in vivo biological response poly (lactic-co-glycolic acid) (PLGA) electrospun membranes incorporated with tea tree oil furan-2(5H)-one. Samples were exposed Strep...

This study investigates the effects of incorporating green and chemical magnetic iron oxide nanoparticles (GMIONPs CMIONPs, respectively) into poly(ε-caprolactone) (PCL) nanofibrous membranes on their physicochemical, mechanical, morphological, functional properties. The evaluates physicochemical optical properties using water contact angle (WCA), vapor permeability (WVP), brightness, color det...

Composite fibrous electrospun membranes based on poly(dl-lactide) (PLA) and poly(ε-caprolactone) (PCL) were engineered to include borate bioactive glass (BBG) for the potential purposes of guided bone regeneration (GBR). The fibers were characterized using scanning and transmission electron microscopies, which respectively confirmed the submicron fibrous arrangement of the membranes and the suc...

A simple, robust, and cost-effective method is developed to fabricate nanofibrous micropatterns particularly microposts and microwells of controlled shapes. The key to this method is the use of an easily micropatternable and intrinsically conductive metal alloy as a template to collect electrospun fibers. The micropatterned alloy allows conformal fiber deposition with high fidelity on its topog...

Polyamide 6 (PA6) was melt-blended with an intumescent flame retardant (FR), multi-wall carbon nanotubes (MWNTs), and nanoclay particles to produce multi-component FR-PA6 nanocomposites. FR-PA6 nanofibers were processed from varied nanocomposite formulations via electrospinning. Electrospinnability, morphology, along with combustion and thermal properties of the nanofibers were investigated. Bo...

Electrospinning was employed to prepare new multi-functional nanowebs. Cyclodextrin based inclusion complex (CD-IC) was used to disperse multiwalled carbon nanotubes (MWNT) within electrospun polyvinylidene fluoride nanofibrous membranes (PVdF-NFM). Subsequently, MWNT(CD-IC)/PVdF-NFM was loaded with gold (Au) particles. The morphology, structure and thermal properties of Au/MWNT(CD-IC)/PVdF-NFM...