BACKGROUND Recent publications have questioned the validity of the "lipid sink" theory of lipid resuscitation while others have identified sink-independent effects and posed alternative mechanisms such as hemodilution. To address these issues, the authors tested the dose-dependent response to intravenous lipid emulsion during reversal of bupivacaine-induced cardiovascular toxicity in vivo. Subs...

Fat is often included in common foods as an emulsion of dispersed oil droplets to enhance the organoleptic quality and stability. The intragastric acid stability of emulsified fat may impact on gastric emptying, satiety and plasma lipid absorption. The aim of the present study was to investigate whether, compared with an acid-unstable emulsion, an acid-stable fat emulsion would empty from the s...

BACKGROUND Aerosolized delivery of antibiotics is hindered by poor penetration within distal and plugged airways. Antibacterial perfluorocarbon ventilation (APV) is a proposed solution in which the lungs are partially or totally filled with perfluorocarbon (PFC) containing emulsified antibiotics. The purpose of this study was to evaluate emulsion stability and rheological, antibacterial, and ph...

Curcumin and catechin are naturally occurring phytochemicals with extreme sensitivity to oxidation and low bioavailability. We fabricated a water-in-oil-in-water (W/O/W) double emulsion encapsulating hydrophilic catechin and hydrophobic curcumin simultaneously. The co-loaded emulsion was fabricated using a two-step emulsification method, and its physicochemical properties were characterised. Vo...

Stable water-in-oil emulsion is essential to digital PCR and many other bioanalytical reactions that employ droplets as microreactors. We developed a novel technology to produce monodisperse emulsion droplets with high efficiency and high throughput using a bench-top centrifuge. Upon centrifugal spinning, the continuous aqueous phase is dispersed into monodisperse droplet jets in air through a ...

We provide evidence of single attoliter oil droplet collisions at the surface of an ultra-microelectrode (UME) by the observation of simultaneous electrochemical current transients (i-t curves) and electrogenerated chemiluminescent (ECL) transients in an oil/water emulsion. An emulsion system based on droplets of toluene and tri-n-propylamine (2:1 v/v) emulsified with an ionic liquid and suspen...

CLINICAL QUESTION Is intravenous lipid emulsion a safe and effective therapy for the reversal and treatment of local anesthetic toxicity? RESULTS Systematic reviews, human case reports, and experimental animal studies have demonstrated the efficacy of intravenous lipid emulsion therapy in successfully reversing cardiac arrhythmias, cardiac arrest, and cardiac collapse seen with severe systemi...

Rigid blade coating of glass plates by oil-in-water emulsions stabilized by surfactants is studied. Complete surface coverage is obtained only for speeds exceeding a threshold velocity dependent on the height between the blade end and the surface. Below this threshold, the emulsion can be inverted in the vicinity of the blade. The inversion dynamics of the oil-in-water emulsion and the depositi...

Ever since C.R.Berry found quantum size effect on nanometer-sized AgX grain and made studies on its anomalous absorption behaviour, much effort has been made on different aspects of nanometer-sized grain emulsion. H.Thiry, M.Iwasaki and his coworkers prepared nanometer-sized AgBr or AgBrI grain emulsion below 30nm scale and made some attempts on spectral sensitization; Investigated the mixture ...