Contemporary research points to infection control as the key determinant of endodontic success. While epidemiological surveys indicate that success is most likely in teeth which have been densely root-filled to within 2 mm of root-end, it is unclear whether the root canal filling itself is a key determinant of outcome. It is also unclear how different materials and methods employed in achieving...

Introduction: Sealing ability of a retrograde filling material is an important factor for a successful endodontic apicoectomy. The purpose of this in-vitro study was to compare the sealing ability of calcium enriched mixture (CEM) cement versus amalgam as root-end filling materials. Methods: A total of 36 canals of extracted maxillary central incisors were instrumented and obturated using later...

To identify mechanisms underlying slow left ventricular filling in coronary artery disease, left ventriculograms from 93 patients and 18 normal subjects were digitised frame by frame and global and regional function analysed. In 54 patients peak normalised filling rates were above the lower 95% confidence limit of normal (2 X 9s-1) and in 39 they were below. Patients with slow filling had a low...

A typical supply chain is an end-to-end process with the main purpose of production, trans‐ portation, and distribution of products. It is relative to the products’ movements from the supplier to the manufacturer, distributor, retailer and finally to the end consumer. More‐ over, a supply chain is a complex amalgam of parties that require coordination, collabora‐ tion, and information exchange ...

AIM The purpose of this investigation was to evaluate the marginal adaptation of five root-end filling materials. METHODS AND MATERIALS Fifty human single-rooted teeth were resected 3 mm from the apex. Root-end cavities were then prepared using an ultrasonic tip and filled with one of the following materials: silver amalgam without zinc, white MTA-Angelus, white Portland cement (PC), Vitremer...

INTRODUCTION Sealing ability is an important factor for a root-end filling material in endodontic surgeries. This in vitro study aimed to compare the sealing ability of mineral trioxide aggregate (MTA) and a new endodontic cement named calcium enriched mixture (CEM) cement as root-end filling materials. MATERIALS AND METHODS The experiments were carried out in dry, saliva or blood contaminate...

Background and aims. Different materials have been used for root-end filling during surgical endodontic treatment. The aim of this in vitro study was to evaluate the dye penetration in different thicknesses of calcium enriched mixture (CEM) cement as root-end filling material. Materials and methods. Following root canal filling in 70 extracted human single-rooted premolar teeth, the apical 3 mm...

AIMS To evaluate the relationships between measures of left ventricular (LV) filling dynamics at cadmium-zinc-telluride (CZT) imaging and indexes of LV diastolic function at transthoracic echocardiography. METHODS AND RESULTS Two hundred and forty-seven patients underwent myocardial perfusion imaging at rest and after stress with a low-dose CZT protocol and a baseline transthoracic echocardio...

The aim of this study was to evaluate in vitro the cytotoxicity on human periodontal ligament fibroblasts of three root-end filling materials: MTA Angelus®, EndoSequence Root Repair Material Putty® and Super EBA®. A primary culture of human periodontal ligament fibroblasts was previously obtained in order to evaluate the cytotoxicity of the three extracts from the root-end filling materials aft...

Non-homologous end joining (NHEJ) is a major pathway for the repair of DNA double strand break (DSBs) with incompatible DNA ends, which are often generated by ionizing irradiation. In vitro reconstitution studies have indicated that NHEJ of incompatible DNA ends requires not only the core steps of synapsis and ligation, employing KU80/DNA-PKcs and LIG4, but also additional DNA end processing st...