the field of endocrine pharmacology is very wide but most of studies in the recent years from the world and iran have focused on diabetes, osteoporosis, and lipid disorders. in the present review, we tried to evaluate the improvements and publications in that field briefly. interestingly, many of studies have focused on agents that have traditional and natural origin. although few basic studies...

The pure anti-oestrogen fulvestrant has now been licensed for use in advanced breast cancer which has progressed on an anti-oestrogen. Optimal sequencing of various endocrine agents becomes very important in the therapeutic strategy. We report our experience of further endocrine response with another endocrine agent after prior fulvestrant treatment. Among all patients with advanced breast canc...

• To recognize the etiologies and clinical manifestations of endocrine crises involving the pancreas, thyroid, adrenal, and pituitary glands • To review the optimal confirmatory laboratory tests for these disorders in the acute care setting • To delineate the initial treatment for each specific endocrine emergency • To cover important pearls and selected caveats related to the diagnosis and man...

background: thalassemia is the most common hereditary anemia and beta thalassemia major is its most severe form. endocrine abnormalities in thalassemia major are common disturbing complications that need prompt management. the purpose of this study was to determine the endocrine disorders and bone mineral density in patients with major -thalassemia in qazvin, iran. methods: in this cross- secti...

the classical triad of mccune-albright syndrome (mas) consists of polyostotic fibrous dysplasia (fd), skin hyperpigmentation (café-au-lait spots), and endocrine dysfunction, frequently seen in females as precocious puberty. etiology is genetically based and is explained by mosaicism of activating somatic mutations of the alpha-subunit of gs protein. clinical presentation is varied and is depend...

We approach the phenomenon of endocrine covfefe through a medical student’s prism. The etiology of endocrine covfefe is multifactorial. Self-styled endocrinologists, practitioners of complementary and alternative medicine (CAM), fitness gurus, manufacturers of non-proven “medicinal” products, and misguided laypersons; all churn out their own version of endocrine fables and myths. The pathogenes...

Law and science combine in the estimation of risks from endocrine disruptors (EDs) and actions for their regulation. For both, dose–response models are the causal link between exposure and probability (or percentage change) of adverse response. The evidence that leads to either regulations or judicial decrees is affected by uncertainty and limited knowledge, raising difficult policy issues that...

Martin W. Adler Edson X. Albuquerque Edmund G. Anderson Lewis Aronow Leslie E. Bailey Paul Bass John A. Bevan C. Paul Bianchi Leslie C. Blaber David A. Blake Floyd E. Bloom Carl K. Buckner Theodore J. Cicero E. E. Daniel William C. de Groat J. W. Downie Linda Dykstra Hugh L. Evans James A. Ferrendelli Lawrence J. Fischer William W. Fleming Ray W. Fuller Gerard L. Gebber James W. Gibb Shri N. Gi...

Reports suggest comorbidity between autism spectrum disorder (ASD) and the connective tissue disorder, Ehlers-Danlos syndrome (EDS). People with EDS and the broader spectrum of Generalized Joint Hypermobility (GJH) often present with immune- and endocrine-mediated conditions. Meanwhile, immune/endocrine dysregulation is a popular theme in autism research. We surveyed a group of ASD women with/w...