PURPOSE Using a noncontact erbium (Er):yttrium--aluminium--garnet (YAG) laser, ablation of vitreous was compared to distilled water in vitro. METHODS The porcine vitreous body and distilled water were ablated in vitro at different pulse lengths and pulse energies. Selected pulse energies were 25, 35, 45, 75, and 100 mJ (pulse rate: 1 Hz; laser beam diameter at the surface of the sample: 2 mm)...

Laser thrombolysis is under investigation as a safe and rapid therapy for arterial recanalization in acute embolic stroke. Clot formation is a complex process affected by many factors that lead to differences in strength and hemoglobin concentration in samples formed from whole blood. The strength of thrombus formed in vivo also varies with age. Laser thrombolysis experiments were performed usi...

Ultrafast laser micromachining is a promising candidate for microand nano-fabrication technology. Due to the high precision of femtosecond ablation, laser-machined features can be added to devices prototyped by lithography. To accomplish that, parametric studies of laser interrogation of materials of interest are necessary. We present femtosecond laser ablation studies of glass, PDMS, fused sil...

The dynamics of damage and ablation of individual particles of ;100 nm in size due to short-pulse laser irradiation is studied using a breathing sphere model and molecular dynamics simulations. The fluence thresholds for damage and ablation of irradiated particles have a strong pulse duration dependence. For 15 ps laser pulses, the laser induced pressure buildup and the focusing of the pressure...

Vocal fold scarring can arise from disease or postsurgical wound healing and is one of the predominant causes of voice disorders. Focused ultrafast laser pulses have been previously demonstrated to create tightly confined sub-surface ablation in a variety of tissue, including vocal folds. Here, we demonstrate how we can take advantage of this unique ability of ultrafast laser ablation to create...

A breathing sphere model has been developed for molecular dynamics simulations of laser ablation of organic solids. The novel feature of this model is an approximate representation of the internal molecular motion, which permits a significant expansion of the time and length scales of the model, and yet still allows one to reproduce a realistic rate of the vibrational relaxation of excited mole...

Laser ablation is the method for material removing from a surface using pulsed lasers. It is used for surface structuring, laser drilling or laser marking. A change of the corrosion behavior of a base material caused by thermal effects during laser processing is an important problem of this technology. Possibilities of surface modification of stainless steel using laser ablation are presented i...

In recent years, due to the demonstrated high accuracy and reproducibility of the surgical procedures with fs pulses, the potential of using fs laser sources as a conventional tool for many surgical applications has increased. Moreover, the laser parameters can be so chosen as to modify the tissue in different ways. Future use of lasers in different fields in medicine will be related with the o...

BACKGROUND Combination of riboflavin/UVA cross-linking (CXL) and excimer laser ablation is a promising therapy for treating corneal ectasia. The cornea is strengthened by cross-linking, while the irregular astigmatism is reduced by laser ablation. This study aims to compare the efficacy of excimer laser ablation on porcine corneas with and without cross-linking. METHODS AND FINDINGS The porci...