Gallstone ileus was first described by Bartholine in 1654, as mechanical intraluminal obstruction, caused by impaction of gallstone in the bowel lumen. The disease occurs more frequently in women than in men, in a ratio of 6:1. And mostly affecting ages over 65 years. Spontaneous biliary enteric fistula was found in 0.9% of patients undergoing biliary tract procedures. In fact, most spontaneous...

AIM To evaluate the NSW enteric disease outbreak surveillance system. EVALUATION METHODS We performed unstructured interviews with NSW Health Communicable Diseases Branch staff and analysed summary outbreak reports for July 2000 to June 2005. PERFORMANCE OF THE SURVEILLANCE SYSTEM: The system provided a mechanism for meeting all of its objectives to some level. Limitations included difficulty...

BACKGROUND Policies and programs are needed to mitigate the burden of enteric disease in Canada. Source attribution, a goal of FoodNet Canada, can inform such strategies and can be accomplished with the information provided by expert opinion. This includes environmental health officers' (EHOs) opinions on the "most likely source of infection" (MLSI) of confirmed cases of enteric disease that ar...

(Macro)-autophagy is a homeostatic process by which eukaryotic cells dispose of protein aggregates and damaged organelles. Autophagy is also used to degrade micro-organisms that invade intracellularly in a process termed xenophagy. Genome-wide association scans have recently identified autophagy genes as conferring susceptibility to Crohn's disease (CD), one of the chronic inflammatory bowel di...

Ulcerative colitis (UC) is a chronic non-specific inflammatory disease affecting the mucosa and the submucosa of the colon, and is characterized by alterations of gut functions which influence the clinical symptoms (Fiocchi, 1998; Reddy et al., 1991; Spriggs et al., 1951). Although reports showed morpho-functional abnormalities of the enteric nervous system in UC patients, the available literat...

Enteric fever, caused by Salmonella enterica serovars Typhi and Paratyphi A (S. Typhi and S. Paratyphi A) remains a major public health problem in many settings. The disease is limited to locations with poor sanitation which facilitates the transmission of the infecting organisms. Efficacious and inexpensive vaccines are available for S. Typhi, yet are not commonly deployed to control the disea...

Ulcerative colitis (UC) is a leading form of inflammatory bowel disease that involves chronic relapsing or progressive inflammation. As a significant proportion of UC patients treated with conventional therapies do not achieve remission, there is a pressing need for the development of more effective therapies. The human gut contains a large, diverse, and dynamic population of microorganisms, co...

The enteric nervous system may have an important role in modulating gastrointestinal barrier response to disease through activation of enteric glia cells. In vitro studies have shown that enteric glia activation improves intestinal epithelial barrier function by altering the expression of tight junction proteins. We hypothesized that severe injury would increase expression of glial fibrillary a...

The primary report of intussusception was made in 1674 by Barbette Amsterdam. It increases the patient's risk intestinal obstruction, parietal ischemia, perforation, and peritonitis. Small submucosal lipomas are an uncommon kind gastrointestinal tumour. is a silent disease that occasionally causes haemorrhage, intussusception, bowel obstruction. Surgery frequently required to confirm diagnosis ...

The authors' objective in this study was to determine geographic variations in the incidence of inflammatory bowel disease (IBD), specifically Crohn's disease and ulcerative colitis, in the Canadian province of Manitoba and its association with the sociodemographic, geographic, and disease-related characteristics of the study population. Using the University of Manitoba IBD Epidemiology Databas...