Recent reports have described the successful treatment of Encephalitozoon intestinalis infection in AIDS patients with albendazole. However, this compound is rapidly metabolized in vivo to albendazole sulfoxide, and furthermore it is only 1 of about 15 commercially developed benzimidazole derivatives. To compare the activities of albendazole, albendazole sulfoxide, and other benzimidazoles, an ...

INTRODUCTION Intestinal parasitic infections have been reported in different regions of Argentina. Giardia intestinalis is recognized as "the national parasite". The aim of this work was to determine the prevalence of both intestinal parasites and G. intestinalis genotypes, as well as to analyze the clinical and epidemiological characteristics in schoolchildren from a suburban community. METH...

Ciona intestinalis is an invasive marine biofouling organism first detected in coastal waters of Newfoundland and Labrador in 2012. As a sessile animal, it is essential that larvae locate a suitable substrate for attachment in an adequate environment, but the timing of this critical event may not be as important as once believed. We demonstrate that while swimming larvae may have limited time t...

Although sensitivity to pollutants is well known be species specific, closely related are often assumed respond similarly them. We tested this assumption, comparing the of Ciona intestinalis and robusta two common marine pollutants: Bisphenol A (BPA) tris(1-chloro-2-propyl)phosphate (TCPP). In particular, we focused on ascidian embryonic development determined whether C. displayed different res...

We herein report N-glycosylation profiles of the individual tissues derived from the ascidian Ciona intestinalis. Multidimensional HPLC mapping revealed that the C. intestinalis expresses high-mannose-type oligosaccharides as major N-glycans, along with paucimannose-type and complex-type oligosaccharides, in a tissue-specific manner. Notably, the trimannosyl core carrying beta1,2-xylose and alp...

The draft genome ( approximately 160 Mb) of the urochordate ascidian Ciona intestinalis has been sequenced by the whole-genome shotgun method and should provide important insights into the origin and evolution of chordates as well as vertebrates. However, because this genomic data has not yet been mapped onto chromosomes, important biological questions including regulation of gene expression at...

Giardia intestinalis has been found in a variety of mammals, including humans, and consists of host-specific and zoonotic genotypes. There has been only 1 study of G. intestinalis infection in weasels, but the genotype of its isolate remains unclear. In this study, we report the isolation of Giardia in a ferret exhibited at a pet shop. The isolate was analyzed genetically to validate the possib...

Bu çalışmada, yeşil alglerden Ulva intestinalis türünün ekolojik özellikleri ile besin kompozisyonundaki değişimin belirlenmesi amaçlanmıştır. Çalışma materyali Sinop kıyıları boyunca seçilen dört farklı noktadan mevsimsel olarak toplanmıştır. Yapılan analizler sonunda mevsimler ve istasyonlar arasında istatistiksel önemli farklılıklar (P

Methanol extracts of leaves, roots and bark of Senna racemosa (Mill.) H.S. Irwin & Barneby (syn. Cassia racemosa Mill.) were tested for antiprotozooal activity against Giardia intestinalis and Entamoeba histolytica. All of the tested extracts showed good activity against both protozoa species. Extracts from stem bark and leaves were most active, with an IC(50) of 2.10 microg/mL for Giardia inte...

Microsporidia are ancient, intracellular, eukaryotic protozoan parasites that form spores and that lack mitochondria. Currently, as many as eight species included under six genera are known to infect humans, mostly patients with AIDS. Among these, Enterocytozoon bieneusi, the agent of gastrointestinal (GI) disease, is the most frequently identified microsporidian in clinical laboratories in the...