BACKGROUND Recent studies in children have demonstrated that frequent occurrence of parasomnias is related to increased sleep disruption, mental disorders, physical harm, sleep disordered breathing, and parental duress. Although there have been several cross-sectional and clinical studies of parasomnias in children, there have been no large, population-based studies using full polysomnography t...

We have investigated two unrelated families, in which two children had inherited primary nocturnal enuresis, and nephrogenic diabetes insipidus caused by new mutations in the aquaporin-2 gene (AQP2). The mutant AQP2 proteins were inactive, suggesting that administration of desmopressin could not concentrate the urine in these patients. However, treatment with desmopressin resolved primary noctu...

Background: This study aimed to evaluate the efficacy of trazodone in the treatment of nocturnal enuresis in school age children. Methods: Nine patients (7 male and 2 female) with nocturnal enuresis, resistant to regular treatments, received trazodone (25 mg/day, for the first week and 50 mg/day for the second week). Results: Marked improvement was observed in one case, while partial improvemen...

Enuresis is a pathologic and bothersome condition, which occurs frequently during childhood (1). Despite the numerous studies that have been conducted to clarify the cause of enuresis, only some of the risk factors for the disease have been found, because “enuresis” is a multifactorial disorder (2). Continence is the result of intact function of bladder to reserve urine during reservation phase...

Background: Enuresis is one of the most common diseases in children. Although there are several factors involved occurrence this diseases, root cause it has remained undetermined. Objectives: Identifying various responsible for enuresis may enormously contribute to solving problem. This study, therefore, aimed determine level vitamin B12 and folic acid children with Gorgan 2021. Methods: In cas...

Guest Comment on Nocturnal Enuresis by Dr. Ankit Mangla, MBBS, MD, FPN, Fellow critical care (IAP/ISCCM), Director & HOD Pediatric Institute of Renal Sciences Senior Consultant, PICU HOPE Hospital, Jaipur

Objectives. Nocturnal enuresis is a common pediatric problem, the etiology of which is unclear. In the present study, vitamin B(12) and folate levels were measured in children with nocturnal enuresis and compared with those in healthy control group children to investigate whether there was any relation with enuresis and neurogenic maturation as a first time in the literature. Methods. In this c...

Method of data collection and synthesis The present statement was last revised in 2002. A PubMed search was conducted for articles published since 1999 to ensure appropriate overlap with the previous review. The search was conducted using the search term ‘Enuresis’, and was limited to ‘Clinical Trials’, ‘Randomized Controlled Trials’ and ‘MetaAnalyses’. In addition, relevant systematic reviews ...