Detection of drugs in a child may be the first objective finding that can be reported in cases of suspected child abuse. Hair and urine toxicology testing, when performed as part of the initial clinical evaluation for suspected child abuse or maltreatment, may serve to facilitate the identification of at-risk children. Furthermore, significant environmental exposure to a drug (considered by law...

Toxicogenomics (TGx), a discipline of toxicology allows scientists to identify and characterize the genomic signatures of environmental toxicants, as well as use gene and protein expression profiles to study the relationship between exposure and disease outcome and understand gene-environment interactions. TGx considered as the fusion of three scientific fields—toxicology, molecular biology and...

DEPARTMENT OF PESTICIDE REGULATION MEDICAL TOXICOLOGY BRANCH SUMMARY OF TOXICOLOGY DATA Trifloxystrobin Chemical Code # 5321, Tolerance # 52415 SB 950 # NA Original: 5/17/00 Revised: 6/26/01 I. DATA GAP STATUS Chronic toxicity, rat: No data gap, no adverse effect Chronic toxicity, dog: No data gap, no adverse effect Oncogenicity, rat: No data gap, no adverse effect Oncogenicity, mouse: No data ...

1 Brain cholinesterase inhibition Toxicology one-liners are attached. All record numbers through 170860 were examined. ** indicates an acceptable study. Bold face indicates a possible adverse effect. ## indicates a study on file but not yet reviewed.

A.D., Wosniok, W. (Eds.), Biological Effects of Contaminants in Pelagic Ecosystems. Society of Environmental Toxicology and Chemistry (SETAC), Brussels, pp. 367–376. Manly, B.F.J., 1998. Randomization, Bootstrap and Monte Carlo Methods in Biology, second ed. Chapman and Hall, London, 399 pp. McCloskey, J.T., Oris, J.T., 1993. Effect of anthracene and solar ultraviolet radiation exposure on gill...

The co-Editors-in-Chief of Environmental Health respond to an unusual initiative taken by editors of 14 toxicology journals to influence pending decisions by the European Commission to establish a framework for regulating chemicals that pose a hazard to normal function of the endocrine system. This initiative is also the subject of this Commentary in this journal by authors who recently reviewe...

Chromosomal effects: No data gap, possible adverse effect DNA damage: No data gap, possible adverse effect Neurotoxicity: Not required at this time 1 Additional information is being requested which will allow reconsideration of data gap status for these study types, based on existing studies. 2 There is no FIFRA-guideline style reproduction study. The "possible adverse effect" reflects informat...

Note: Toxicology one-liners are attached Note: In one liner volume/record number citations below: ** indicates acceptable study Bold face indicates possible adverse effect This revision considers all submissions with record numbers up to 160342 (Document 380-154). These include all records on file as of 7/01/98. Record numbers greater than 900,000 have also been reviewed, where appropriate. Ald...

DEPARTMENT OF PESTICIDE REGULATION MEDICAL TOXICOLOGY BRANCH SUMMARY OF TOXICOLOGY DATA DIAZINON Chemical Code # 198, SB 950-204, Tolerance # 00153 July 29, 1986 Revised 6/16/88, 2/17/89, 2/27/90, 12/28/93, 8/20/96, 7/21/98, 4/15/99 I. DATA GAP STATUS Chronic toxicity, rat: No data gap, no adverse effect Chronic toxicity, dog: No data gap, no adverse effect Oncogenicity, rat: No data gap, no ad...