Charge sensors based on nanoscale field-effect transistors are a promising new tool to probe the dynamics of individual enzymes. However, it is currently unknown whether the electrostatic signals associated with biological activity exceed detection limits. We report calculations of electrostatic signatures of two representative enzymes, deoxyribonuclease I and T4 lysozyme. Our simulations revea...

We prepared rod-shaped gold nanorattles solid gold nanorods surrounded by a thin gold shell using a galvanic replacement process starting with silver-coated gold nanorods. These structures are very promising candidates for catalytic applications and optimized plasmon sensors. They combine the advantages of rods (low plasmon resonance frequency, large polarizability, small damping) with the high...

In order to get a methane catalytic combustion micro-sensor, two different catalytic systems used in traditional methane catalytic combustion sensors were fabricated into a mesoporous structure and their catalytic activities were investigated. In comparison, the Rh2O3-Al2O3 system can form more a uniform mesoporous structure and has a much higher specific surface area. Even more importantly, it...

Wireless sensor networks (WSNs) have many applications in the areas of commercial, military and environmental requirements. Regarding the deployment of low cost sensor nodes with restricted energy resources, these networks face a lot of security challenges. A basic approach for preparing a secure wireless communication in WSNs, is to propose an efficient cryptographic key management protocol be...

In this work, two methods with complementary features, catalytic and molecular beacon (CAMB) and label-free fluorescent sensors using an abasic site, have been combined into new label-free CAMB sensors that possess advantages of each method. The label-free method using a dSpacer-containing molecular beacon makes CAMB more cost-effective and less interfering with the catalytic activity, while CA...

In this paper, we report on demonstration of digital counting of enzyme based on fluorescent femtoliter droplet array imaging by using a lensless CMOS image sensor. The result supports the device can be applied to digital enzyme linked immunosorbent assay (ELISA). Digital ELISA is an ultra-sensitive detection technique for a biomarker [1, 2]. In the previous work, we developed a miniature lensl...

cupric oxide nanostructures were synthesized via a simple reaction between copper nitrate and sodium hydroxide using a sonochemical-assisted method. the synthesized cuo was then characterized using x-ray diffraction, scanning electron microscopy, transmission electron microscopy, fourier transform infrared, ultraviolet-visible and photoluminescence spectroscopy. our studies show that the cuo na...