In our previous work, we have identified, in a model wine solution containing malvidin 3-glucoside, epicatechin and acetaldehyde, a new condensation product--hydroxylethyl-malvidin-3-glucoside-ethyl-epicatechin. The objective of this work was to verify the presence of such new condensation products in red wine. For this purpose, red wine was fractionated into various fractions by column chromat...

Grapes are one of the most widely grown fruits and have been used for winemaking since the ancient Greek and Roman civilizations. Grape seeds are rich in proanthocyanidins which have been shown to possess potent free radical scavenging activity. Grape seeds are a complex matrix containing 40% fiber, 16% oil, 11% proteins, and 7% complex phenols such as tannins. Grape seeds are rich sources of f...

A SIGNIFICANT NUMBER OF EPIDEMIOLOGICAL studies report on the apparent beneficial effects of chocolate (i.e., cocoa) consumption on cardiovascular health, including reductions in morbidity and mortality (1, 2, 4). However, these reports are mostly of retrospective nature and do not demonstrate causality. Thus the need to implement well-designed prospective studies that unequivocally demonstrate...

PURPOSE Green tea has been shown to exhibit cancer-preventive activities in preclinical studies. Its consumption has been associated with decreased risk of certain types of cancers in humans. The oral bioavailability of the major green tea constituents, green tea catechins, is low, resulting in systemic catechin levels in humans many fold less than the effective concentrations determined in in ...

Background/Aim: The flavonoid quercetin exerts significant anti-inflammatory activity against chronic infections, including periodontal disease. However, it is unclear whether combination of quercetin with other flavonoids enhances antioxidant and anti-inflammatory activity. To clarify the molecular mechanism responsible for the anti-inflammatory activity of quercetin, we investigated the antio...

Abstract Epimerization can change the catechin content and composition of samples during extraction analytical analyses. To control effect epimerization, we developed a novel stable isotope dilution liquid chromatography-mass spectrometry (LC–MS) method using catechin-2,3,4- 13 C 3 epicatechin-2,3,4- as stable-isotope-labeled internal standards (SIL-ISs). When SIL-ISs were used, epicatechin con...

Aim: The aim of the study was Identification and quantification phenolic compounds, total flavonoides content antioxidant potential flower buds, foliages, bark root a perennial herb, Calligonum polygonoides (Phog) Thar Desert. Methodology: methanolic extracts different plant parts C. were subjected to LC-MS/MS (Waters Acquity UPLC-PDA, TQD) analysis for identification spectrophotometric assay f...