Five years after the apparent end of the major 1995 Venezuelan equine encephalitis (VEE) epizootic/epidemic, focal outbreaks of equine encephalitis occurred in Carabobo and Barinas States of western Venezuela. Virus isolates from horses in each location were nearly identical in sequence to 1995 isolates, which suggests natural persistence of subtype IC VEE virus (VEEV) strains in a genetically ...

ion of an SAP system (CI: central instance; DI: dialog instance). 4 : 4 B. ROCHWERGER ET AL. IBM J. RES. & DEV. VOL. 53 NO. 4 PAPER 4 2009 service applications based on a formal contract that specifies the infrastructure SLAs. The same contract should be reused to provision multiple instances of the same application for different tenants with different customizations. Dynamic elasticity—The Res...

The use of random samples to approximate properties of geometric configurations has been an influential idea for both combinatorial and algorithmic purposes. This chapter considers two related notions—ǫ-approximations and ǫ-nets—that capture the most important quantitative properties that one would expect from a random sample with respect to an underlying geometric configuration. An example pro...

We give a $(1+\epsilon)$-approximate distance oracle with $O(1)$ query time for an undirected planar graph $G$ with $n$ vertices and non-negative edge lengths. For $\epsilon>0$ and any two vertices $u$ and $v$ in $G$, our oracle gives a distance $\tilde{d}(u,v)$ with stretch $(1+\epsilon)$ in $O(1)$ time. The oracle has size $O(n\log n ((\log n)/\epsilon+f(\epsilon)))$ and pre-processing time $...

We developed a method to estimate genotype-specific average relative mortality risk, R, from genotype distributions in cross-sectional studies of people belonging to different age-groups, and applied the method to new data from a study of apolipoprotein E genotypes (apoE) in 177 Danish centenarians and data from a study of 40-year-old Danish men. Twenty-one percent of the centenarians were epsi...

Genotoxic activities of a series of commercially purchased 1,N6-ethenoadenosine (epsilon-Ado) and epsilon-deoxyadenosine (epsilon-dAdo) derivatives were assessed using the sister chromatid exchange (SCE) assay in murine spleen lymphocytes in vitro. Of the epsilon-Ado adducts evaluated for SCE induction epsilon-ATP and epsilon-dATP were highly active (5x baseline) SCE inducers over a concentrati...

We review the current status of calculations of the two pion decays of the kaon using the firstprinciples methods of lattice gauge theory and the significant challenges that these calculations pose. While a calculation with controlled errors at even the 10-20% level has not yet been performed, present results suggest that such a calculation of the real and imaginary parts of the ∆I = 3/2 amplit...

vspace{0.2cm}In this paper, we design a data structure for the following problem. Let $pi$ be an $x$-monotone trajectory with $n$ vertices in the plane and $epsilon >0$. We show how to preprocess $pi$ and $epsilon$ into a data structure such that for any horizontal query segment $Q$ in the plane, one can quickly determine the minimal continuous fraction of $pi$ whose Fr{'e}chet and Hausdo...

The use of random samples to approximate properties of geometric configurations has been an influential idea for both combinatorial and algorithmic purposes. This chapter considers two related notions— -approximations and -nets—that capture the most important quantitative properties that one would expect from a random sample with respect to an underlying geometric configuration. An example prob...

A population of cells that express mast cell markers, including the membrane protein p161, but that lack expression of the high affinity IgE receptor, Fc epsilon RI, can be routinely grown from bone marrow. Ionomycin, but not IgE immune complexes, causes these cells to release serotonin and to express IL-3 and IL-13 mRNA, consistent with their being FC epsilon RI-deficient mast cells. These p16...