Mediator is a modular multiprotein complex required for regulated transcription by RNA polymerase (Pol) II. Here, we show that the middle module of the Mediator core contains a submodule of unique structure and function that comprises the N-terminal part of subunit Med7 (Med7N) and the highly conserved subunit Med31 (Soh1). The Med7N/31 submodule shows a conserved novel fold, with two proline-r...

Invertibility of multiplication modules All rings are commutative with 1 and all modules are unital. Let R be a ring and M an R-module. M is called multiplication if for each submodule N of M, N=IM for some ideal I of R. Multiplication modules have recently received considerable attention during the last twenty years. In this talk we give the de nition of invertible submodules as a natural gene...

The concept of the Extend Nearly Pseudo Quasi-2-Absorbing submodules was recently introduced by Omar A. Abdullah and Haibat K. Mohammadali in 2022, where he studies this it is relationship to previous generalizationsm especially 2-Absorbing submodule submodule, addition studying most important Propositions, charactarizations Examples. Now research, which considered a continuation definition tha...

A right Johns ring is a Noetherian in which every ideal annihilator. It known that RR the Jacobson radical J(R)J(R) of nilpotent and Soc(R)(R) an essential RR. Moreover, Kasch, is, simple RR-module can be embedded For M∈RM∈R-Mod we use concept MM-annihilator define module (resp. quasi-Johns) as MM such submodule MM-annihilator. called quasi-Johns if any set submodules satisfies ascending chain ...

Negative cofactor 2 (NC2) has been described as an essential and evolutionarily conserved transcriptional repressor, although in vitro and in vivo experiments suggest that it can function as both a positive and a negative effector of transcription. NC2 operates by interacting with the core promoter and components of the basal transcription machinery, like the TATA-binding protein (TBP). In this...

‎Let $R$ be commutative ring with identity and $M$ be an $R$-module‎. ‎The zero divisor graph of $M$ is denoted $Gamma{(M)}$‎. ‎In this study‎, ‎we are going to generalize the zero divisor graph $Gamma(M)$ to submodule-based zero divisor graph $Gamma(M‎, ‎N)$ by replacing elements whose product is zero with elements whose product is in some submodules $N$ of $M$‎. ‎The main objective of this pa...

Our dual notions “locally injective” and “locally projective” modules in Mod-R are good tools to study the relations between the singular, respectively cosingular, submodule of Hom R(M, W ) and the total Tot (M, W ). These notions have further interesting properties.