Cysteine plays a key role as a metal ligand in metalloproteins. In all well-recognized cases, however, it is the anionic cysteinate that coordinates. Several cysteinate-ligated heme proteins are known, but some fail to retain thiolate ligation in the ferrous state, possibly following protonation to form neutral cysteine. Ligation by cysteine thiol in ferrous heme proteins has not been documente...

The crystal and molecular structures of 4-ethyl-3,5-dimethylpyrrole-2-carbaldehyde, C10H15NO, (I), benzyl 3,5-dimethylpyrrole-2-carboxylate, C14H15NO2, (II), benzyl 4-acetyl-3,5-dimethylpyrrole-2-carboxylate, C16H17NO3, (III), dimethyl 3,5-dimethylpyrrole-2,4-dicarboxylate, C10H13NO4, (IV), 4-ethyl-3,5-dimethyl-2-(p-tosylacetyl)pyrrole, C17H21NO3S, (V), and ethyl 4-(2-ethoxycarbonyl-2-hydroxyac...

Two prenylated biflavonoids, podoverines B-C, were isolated from the dried roots and rhizomes of Sinopodophyllum emodi using a Sephadex LH-20 column (SLHC) and high-speed counter-current chromatography (HSCCC). The 95% ethanol extract was partitioned with ethyl acetate in water. Target compounds from the ethyl acetate fraction were further enriched and purified by the combined application of SL...

Two new trihydroxy derivative of Δ8(14),15-isopimarane diterpenoids, shanpanootols G (1) and H (2), along with three known analogues were isolated from the ethyl acetate-soluble extract Kaempferia pulchra rhizomes collected in Shan State Myanmar. The structures these compounds including their absolute configurations elucidated by combination one dimensional (1D) 2D-NMR spectroscopic methods, hi...

We investigated behavior, physiology, sensitivity to exogenous application of ecdysone, and nerve terminal structure for differences between the reduced ecdysone genotype, ecd(1)/ecd(1), and wild-type control ecd(1)/TM6B animals during the early and late third instars when raised at 25 degrees C. The ecd(1) mutants were able to survive through larval development and form pupae. However, the res...

In the mol-ecule of the title compound, C(18)H(12)N(2)OS, the tetra-hydro-benzo[h]quinoline fused-ring system is buckled owing to the ethyl-ene -CH(2)CH(2)- fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine ring by 59.5 (2)° (for the major disordered thienyl component) in order to avoid crowding the cyanid...

mnco2o4 (mno-co2o3) nanocomposite as a binary oxide has been successfully prepared by precipitation method using cobalt nitrate and manganese nitrate as the precursors and then characterized by scanning electron microscopy-energy dispersive micro-analysis (sem-edx) and x-ray diffraction (xrd) techniques. in this work, we report the hydrolysis kinetics reactions of semi mustard (chloroethyl ethy...

The title compound, C(14)H(15)NO(4), was prepared by a 1,3-dipolar cyclo-addition from N-(eth-oxy-carbonyl-methy)pyridinium bromide and ethyl acrylate. The -CO(2) side chains form dihedral angles of 0.2 (3) and 2.4 (3)° with respect to the ring system. In the crystal, two neighbouring mol-ecules form a dimer through weak C-H⋯O interactions. The dimers form a three-dimensional structure via furt...