The homodimers of transiently chiral molecules offer physical insight into the process molecular recognition, preference for homo or heterochiral aggregation and nature non-covalent interactions stabilizing adducts. We report observation benzyl mercaptan dimer in isolation conditions a supersonic jet expansion, using broadband (chirped-pulse) microwave spectroscopy. A single homochiral isomer w...

Admixture of separated L and H polypeptide chains of 7S gamma-globulins under appropriate conditions has been found to result in the reconstitution of 7S molecules. The chains were mixed in 0.5 N propionic acid and when dialyzed into neutral aqueous buffers interacted to form reconstituted material in greater than 30 per cent yield. This material had sedimentation coefficients of 6S to 7S, a we...

Halitosis occurs in approximately 30% of the adult population and has a negative social and psychological impact on affected individuals. Mouthwashes may be used to prevent unpleasant odour, with long-duration of effect being a desirable attribute. The aim of this study was to assess the long-term efficacy of CB12 (a mixture of 0.3% zinc acetate and 0.025% chlorhexidine) for the treatment of in...

nifedipine (nif), a 1,4-dihydropyridine calcium channel antagonist, undergoes photo-degradation to dehydro-nifedipine (dnif) upon exposure to ultraviolet (uv) light and to the nitroso analogue of dehydro-nifedipine (ndnif) when exposed to sunlight or some kinds of artificial lights. nif photo-degradation products do not contribute to clinical activity, thus prevention of photo-degradation of ni...