The transcription factor Ets-1 plays several distinct critical roles in tumour development and progression by acting both in neoplastic cells and in the tumour stroma. Increased expression of Ets-1 in tumours is often associated with a worse prognosis. Stromal fibroblasts attribute an important part to the behaviour of malignant tumours. In this study we investigated the role of Ets-1 in the tu...

Perinatal environmental tobacco smoke (ETS) exposure in humans elicits neurobehavioral deficits. We exposed rhesus monkeys to ETS during gestation and through 13 months postnatally, or postnatally only (6-13 months). At the conclusion of exposure, we examined cerebrocortical regions and the midbrain for cell damage markers and lipid peroxidation. For perinatal ETS, two archetypal patterns were ...

This thesis presents an initial application of the Evolving Transformation System (ETS) formalism to the structural representation of Russian fairy tales. This work was motivated by the needs of information retrieval (IR) in general, but specifically concentrates on proposing a new type of document representation. The new representation is based on the temporal or constructive process of events...

We examined the correlation between the odor concentration and the chemical composition of environmental tobacco smoke (ETS). Three types of ETS samples were prepared: secondhand smoke (SHS), thirdhand smoke (THS), and field ETS samples from an outside smoking area. The odor concentrations of the ETS, SHS, and THS samples were determined by the triangle-odor-bag method, and the chemical composi...

The Johns Hopkins University School of Hygiene and Public convened a multidisciplinary workshop 12-13 September 1997 to assess current understanding of environmental tobacco smoke (ETS) exposure in the workplace. Invited participants represented areas of expertise in building systems, measurement of ETS, biomarkers of ETS exposure, time-activity patterns, and exposure models. Workshop participa...

The upcoming European Emissions Trading Scheme (ETS) is one of the more controversial climate policy instruments. Predictions about its likely impact and its performance can at present only be made to a certain degree. As long as the National Allocations Plans are not finally settled the overall supply of allowances is not determined. In this paper, we will identify key features and key impacts...

To understand the role of the Ets-1 transcription factor during angiogenesis, we have overexpressed it in endothelial cells and analyzed the levels of expression of several candidate target genes involved in angiogenesis. The transcripts levels of the ETS transcription factor fli-1 are specifically up-regulated in endothelial cells, which overexpress Ets-1, but not in fibroblasts. Analysis of t...

The expression of androgen receptor (AR) has been detected in hepatocellular cancer (HCC). However, there is no universal model detailing AR's function and mechanism in HCC. This study's results show that treatment with dihydrotestosterone (DHT), an endogenous androgen, promoted HCC cells' proliferation and up-regulated the transcription factor activity of ETS-1 (E26 transformation specific seq...

OBJECTIVE To test the hypothesis that environmental tobacco smoke (ETS) exposure is inversely associated with socioeconomic status. DESIGN Survey. SETTING General community, New Zealand. PARTICIPANTS 7725 non-smoking adults (volunteer sample of a multi-industry workforce, n = 5564; and a random sample of urban electoral rolls, n = 2161), including 5408 males; mean age 45 years. MAIN OUT...

OBJECTIVE To test the immunohistochemical staining pattern of some mismatch repair (MMR) system proteins in endometriotic tissue (ET) and eutopic endometrium. METHODS This was a retrospective study conducted at the Pathology and Obstetrics and Gynecology Departments of the Udine University Hospital. We analyzed 528 samples obtained from 246 patients affected by endometriosis and 71 samples fr...