نتایج جستجو برای: excision
تعداد نتایج: 42469 فیلتر نتایج به سال:
Journal:
:Cold Spring Harbor Perspectives in Biology
2013
Journal:
:Cancer research
2002
Tonko Buterin
Martin T Hess
Daniela Gunz
Nicholas E Geacintov
Leon H Mullenders
Hanspeter Naegeli
Nucleotide excision repair is part of a cellular defense system that protects genome integrity.Here, this versatile repair system was challenged with mixtures of DNA adducts that were generated to mimic the wide spectrum of bulky lesions produced by complex genotoxic insults. Probing human excision activity with substrate combinations instead of single lesions resulted in a strong bias for part...
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