نتایج جستجو برای: exon gene
تعداد نتایج: 1147509 فیلتر نتایج به سال:
In recent years, RNA-seq is emerging as a powerful technology in estimation of gene and/or transcript expression, and RPKM (Reads Per Kilobase per Million reads) is widely used to represent the relative abundance of mRNAs for a gene. In general, the methods for gene quantification can be largely divided into two categories: transcript-based approach and 'union exon'-based approach. Transcript-b...
p53 gene is one of the most tumor suppressor genes that causes more than 50 percent of the human cancers. Considering the daily rise in the incidence of breast cancer in various parts of the world , including Iran , there was a great need for a molecular study for determination of P53 ...
OBJECTIVE In order to complete the knowledge of the genomic organization of the human thyroglobulin gene, the present work was designed to establish the intron-exon organization from exon 24 to exon 35 and to construct a more complete physical map of the gene. DESIGN Screening of two genomic libraries, and subsequent restriction mapping, hybridization and sequencing were used to characterize ...
Introduction: Breast cancer is the most common malignancy in women worldwide. BRCA1 is a tumor suppressor gene that is involved in DNA-damage repair. One of the significant risk factors of breast cancer is the family history. BRCA1 gene consists of 24 exons that encode a protein with 1863 amino acids. Exon 11 is the largest exons and most of the disease-linked mutations have been found in it. I...
Signaling pathways are controlled by a vast array of posttranslational mechanisms. By contrast, little is known regarding the mechanisms that regulate the expression of their core components. We conducted an RNAi screen in Drosophila for factors modulating RAS/MAPK signaling and identified the Exon Junction Complex (EJC) as a key element of this pathway. The EJC binds the exon-exon junctions of...
Joubert syndrome (JS) is a rare autosomal recessive neurodevelopmental disorder characterized by hypotonia, ataxia, developmental delay, intellectual disability, abnormal eye movements and breathing pattern. It has variable phenotype which makes it difficult to diagnose. We presented case of 14 month old girl with delayed milestones feeding difficulties. MRI brain this patient in contrast the c...
Objectives: Royal jelly (RJ), a secretion of both the hypopharyngeal and mandibular glands of nurse workers, is believed to play a central role in honeybee queen development. Important component of royal jelly are proteins which form about 50% of the dry mass of RJ. Major royal jelly proteins (MRJPs) are the dominant proteinaceous component of royal jelly and constitute about 82-90% of total pr...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید