Periodontitis is a chronic inflammation of the periodontium caused by persistent bacterial infection that leads to the breakdown of connective tissue and bone. Because the ability to reconstruct the periodontium is limited after alveolar bone loss, early diagnosis and intervention should be the primary goals of periodontal treatment. However, periodontitis often progresses without noticeable sy...

PURPOSE To describe the profile of chronic and aggressive periodontitis among Senegalese (West Africans) attending the Institute of Dentistry of Dakar. METHODS A retrospective study was conducted with an inclusion period running from 2001 to 2008. The sample included 413 chronic periodontitis and 151 aggressive periodontitis cases, among them 299 males and 265 females selected from 2,274 reco...

BACKGROUND The prevalence of diabetes mellitus type 2 (DM2) in Indonesia is high and still rising. Periodontitis is associated with DM2. No study has investigated this association in Indonesia, nor has any study investigated this association using a variety of methods to operationalize periodontitis. The present study compares prevalence and severity of periodontitis in patients with DM2 to hea...

statement of problem: changes in protein levels, host calls enzymes and inflammatory mediators in gingival crevicular fluid (gcf) are considered as diagnostic indicators of periodontitis.purpose: he aim of the present study was to measure the elastase enzyme activity in gingival crevicular fluid among patients with periodontitis.material and methods: in this study, 52 periodontitis patients (ex...

background: this study compared the effect of adjunctive low dose doxycycline and licorice on gingival crevicular fluid (gcf) matrix metalloproteinase-8 (mmp-8) levels in patients with chronic periodontitis. materials and methods: in this in vivo , experimental study 39 patients with mild to moderate chronic periodontitis were selected. samples of gcf were collected from three deepest pockets a...

Associate Professor of Cardiac Surgery at the Campinas State University Medical School. E-mail: [email protected] Cardiovascular diseases, especially those associated with atherosclerosis, are still one of the main causes of death worldwide. There are well-established risk factors for cardiovascular diseases, one of them being elevated levels of serum lipids combined with infections such as odonto...

Periodontitis is a polymicrobial oral infection characterized by the destruction of tooth-supporting structures that can be linked to systemic diseases such as cardiovascular disease, diabetes or rheumatoid arthritis. Porphyromonas gingivalis, a bacterium implicated in the etiology of periodontitis, has shown variation in inducing T-cell responses among different strains. Therefore, in this stu...

The non-antimicrobial properties of tetracyclines such as anti-inflammatory, proanabolic and anti-catabolic actions make them effective pharmaceuticals for the adjunctive management of chronic inflammatory diseases. An over-exuberant inflammatory response to an antigenic trigger in periodontitis and other chronic inflammatory diseases could contribute to an autoimmune element in disease progres...