1 Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 14490, Bogotá, D.C, Colombia. 571-3165000 ext. 14662 2 Instituto Universitario de Bio-Orgánca “Antonio González”, Universidad de La Laguna, Avda. Astrofísico. Francisco Sánchez 2, La Laguna, 38206, Tenerife, Islas Canarias, España 3 Instituto de Química y Fisicoquímica Biológicas, Facultad de Farmacia y Bio...

Cystic fibrosis (CF), the most common life-shortening genetic disorder in Caucasians, affects approximately 70 000 individuals worldwide. In 1998, the Cystic Fibrosis Foundation (CFF) launched the CF Therapeutics Development Network (CF-TDN) as a central element of its Therapeutics Development Programme. Designed to accelerate the clinical evaluation of new therapies needed to fulfil the CFF mi...

Article history: Received 5 June 2009 Available online xxxx Submitted by Goong Chen

cystic fibrosis (cf) is a life-limiting autosomal recessive disorder affecting principally respiratory and digestive system . it is caused by cystic fibrosis transmembrane conductance regulator (cftr) gene mutation. the aim of this study was to determine the extent of repeat numbers and the degree of heterozygosity for c.3499+200ta(7_56) and d7s523 located in intron 17b and 1 cm proximal to the...

Fulfilling the production objectives of a grassland-based beef system requires a robust management strategy to secure the best practicable use of forage resources with regard to the cattle demand. To address the challenging issue of designing such strategies, this article describes the application of an ontology of agricultural production systems to the generic conceptual model SEDIVER, which s...