BACKGROUND Several animal models have facilitated the evaluation and pathological understanding of atherosclerosis, but a definitive animal model of coronary atherosclerosis is not available. We therefore developed low density lipoprotein receptor knockout (LDLR-KO) pigs with hypercholesterolemia, a model which rapidly developed coronary atherosclerosis following balloon injury. METHODS AND R...

the modified nrtl (m-nrtl) model is used to represent the excess gibbs free energy of aqueous (alcohol + electrolyte) solutions. in this work, the m-nrtl model previously developed for representation of vapor-liquid equilibria for (polymer + salt + water) systems has been extended to represent liquid-liquid equilibria of (alcohol + salt + water) systems. the proposed extension is a modified of ...

Introduction: Mitral stenosis is a prevalent valvular disease in developing countries. Percutaneous mitral balloon valvuloplasty (PMBV) is the gold standard treatment. The main objective of this study was to assess the initial results of PMBV in patients with mitral stenosis during 16 years (2002-2018) in Mashhad, Iran. Materials and Methods: From April 2002 to March 2018, 770 patients underwen...

Data Envelopment Analysis (DEA) models with interval inputs and outputs have been rarely discussed in DEA literature. This paper, using the enhanced Russell measurement proposes an extended model which permits the presence of interval scale variables which can take both negative and positive values. The model is compared with most well-known DEA models of which include the CCR model, the BCC mo...

Physiological and biophysical models have been proposed to link neural activity to the Blood Oxygen Level-Dependent (BOLD) signal in functional MRI (fMRI). They rely on a set of parameter values that cannot always be extracted from the literature. Their estimation is challenging because there are more than 10 potentially interesting parameters involved in non-linear equations and whose interact...

Cardiovascular diseases are the main cause of death in Germany. A long-term blood pressure measurement is crucial to identify hypertension which can lead to cardiovascular disease. Conventional techniques use the automatic arm cuff method which is painful and provides only intermittent results. A new method for continuous measurement is developed using a DOPPLER ultrasound sensor on a superfici...

Percutaneous revascularization as an alternative to surgery in the management of peripheral vascular disease was first described in 1964 but gained little acceptance.' In 1974 the development of a doublelumen balloon catheter by Gruntzig and others made the technique a much more practical and effective one that has subsequently gained widespread acceptance.2 At first it was used in the peripher...