Though rare amongst stomach neoplasms, primary gastric diffuse large B cell lymphoma is one of the commonest extranodal non-Hodgkin lymphomas. If left untreated, it can have a devastating progression and life-threatening consequences. We present the case of a successfully treated large antral ulcer confirmed to be large B cell lymphoma as evidenced by radiologic, endoscopic and histopathologic ...

Mantle cell lymphoma is a type of non-Hodgkin lymphoma that affects extranodal areas, especially, bone narrow, digestive tract and Waldeyer ring. Here we report a case of mantle cell lymphoma IV Ann Arbor stage with cutaneous lesions on nasal dorsum and glans penis as the first manifestations. Skin involvement is a very rare manifestation and less than 20 cases have been reported in the literat...

Hepatosplenic T-cell lymphoma (HSTL) is rare, being derived from cytotoxic T-cells, and manifests as an extranodal systemic lymphoma. We present an unusual case of a seventeen-year-old female, with no significant prior medical history, presenting with a hepatosplenic T-cell lymphoma. The diagnosis was confirmed by histological examination, immunohistochemisty, and flow cytometry. A staging work...

This consensus report of the EGILS (European Gastro-Intestinal Lymphoma Study) group includes recommendations on the management of gastric extranodal marginal zone B-cell lymphoma of MALT. They are based on data from the literature and on intensive discussions and votings of the experts during their annual meetings.

A nasal-type extranodal natural killer/T-cell lymphoma is considered an aggressive form of non-Hodgkin's lymphoma, with approximately half of all patients relapsing during the follow-up period, and most relapses occurring within the first 2 years of remission. Here we report an unusual case of a 42-year-old man who experienced recurrence in single pleura after 8 years of remission.

Mucosa-associated lymphoid tissue lymphoma (MALToma) is a low grade B-cell lymphoma that develops from the lungs, intestinal tract, salivary gland, and other organs and is included under extranodal marginal zone lymphoma. When a primary pulmonary MALToma develops from bronchus-associated lymphoid tissue (BALT), it is called BALT lymphoma (BALToma). The etiology of MALToma is not clear; however,...

OBJECTIVE Extranodal involvement represents a peculiar presentation of diffuse large B-cell lymphoma (DLBCL). Previous studies have suggested that older patients are more prone to extranodal involvement. This study retrospectively addressed the distribution, prognostic value and treatment options of extranodal involvement in young patients with DLBCL. METHODS A total of 329 patients were enro...

Primary extranodal lymphoma is a common malignant tumor of head and neck but rarely presents in lateral skull base. We reported such a case of lymphoma categorized as diffuse large B-cell lymphoma (DLBCL) subtype in a 74-year-old Chinese female. She has experienced an acute course of continuously trigeminal neuralgia and Horner's syndrome. The lesion was diagnosed as trigeminal schwannoma based...

Indolent breast lymphomas (IBL) are a rare form of extranodal lymphoma. There are very few reported cases of IBL presenting as a breast mass. We report two cases of IBL, a Marginal Zone Lymphoma (MZL) and a Small Lymphocytic Lymphoma (SLL), which were discovered on routine mammogram and later confirmed by biopsy and flow cytometery. Patient with MZL underwent chemotherapy and radiation therapy ...

A median 80 months follow-up with updated time to progression (TTP) and survival data is presented from a multicenter phase II trial using 2-Chlorodeoxyadenosine (2-CdA) in the treatment of extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue type (MALT lymphoma) [1]. With the exception of Helicobacter pylori (HP) eradication therapy in localized gastric disease no ...