BACKGROUND While standardized methods are established to examine the pathway from motorcortex to the peripheral nerve in patients with facial palsy, a reliable method to evaluate the facial muscles in patients with long-term palsy for therapy planning is lacking. METHODS A 3D ultrasonographic (US) acquisition system driven by a motorized linear mover combined with conventional US probe was us...

PURPOSE To search for a new definition of muscle hypoplasia in congenital or idiopathic superior oblique muscle palsy. DESIGN Retrospective case-control study. METHODS Cross-sectional areas of the superior oblique and 4 rectus muscles near the eye globe-optic nerve junction were measured by an image analysis software on magnetic resonance images of 50 patients with congenital or idiopathic ...

Abstract Purpose of Review To provide the radiologist with tools to recognize findings atypical for Graves’ ophthalmopathy and differentiate between most important common alternative causes extraocular muscle enlargement on CT MR imaging. Recent We introduce five ‘red flags’ representing features that are ophthalmopathy: unilateral disease, pattern involvement, adjacent structure restricted dif...

PURPOSE PITX2 gene dose plays a central role in Axenfeld-Rieger syndrome. The purpose of this study was to test the hypothesis that the effects of Pitx2 gene dose on eye development can be molecularly dissected in available Pitx2 mutant mice. METHODS A panel of mice with Pitx2 gene dose ranging from wild-type (+/+) to none (-/-) was generated. Eye morphogenesis was assessed in animals with ea...

A 31-year-old patient had acute dizziness and lateropulsion to the right. Neuro-ophthalmologic examination revealed (1) a saccade gaze palsy left (video 1, part A), (2) “half-pathologic” head-impulse test right B), but (3) bilaterally normal adduction during convergence reaction C), findings typical for abducens nuclear palsy. It was caused by histologically proven cavernoma in tegmentum pontis...

Cases of congenital ptosis are rare, that too occurring in twins. We presenting a case mono zygotic twins with bilateral fibrosis extraocular muscles (CFEOM). A 5-year-old boy child and his twin brother who monozygotic presented ptosis. Both children had been diagnosed as having Parents have refused surgical intervention for the muscle weakness. They were advised, if complained any visual abnor...

PURPOSE Although alteration in hypertropia induced by head tilt is considered a clinical criterion for diagnosis of superior oblique (SO) palsy, the mechanism of this head-tilt-dependent hypertropia (HTDHT) is unclear. In this study, magnetic resonance imaging (MRI) was used to study extraocular muscle (EOM) responses to head tilt in HTDHT. METHODS Orbital MRI was used to study 16 normal subj...

purpose: to evaluate the incidence of the oculo-cardiac reflex (ocr) and its associated risk factors during strabismus surgeries performed at a tertiary referral center between 1390 and 1392. methods: over a 2-year period, all strabismus surgery candidates were enrolled in the study after obtaining consent from the patients or their parents. vital signs were recorded before the initiation of th...

The saccadic system accurately compensates for perturbations of eye position produced by microstimulation of the superior colliculus. This requires that information about the stimulation-induced change in eye position be provided by an extraretinal source--either proprioceptive endings in extraocular muscles or a centrally generated corollary discharge. It is shown that compensation remains int...

Proptosis and diplopia due to enlargement of extraocular muscles represent important presenting signs of many orbital disorders. Although dysthyroid ophthalmopathy is the most common cause of enlargement of extraocular muscles, the differential diagnosis is extensive. We report a patient with a 3-month history of diplopia and unilateral proptosis and a markedly enlarged inferior rectus muscle o...