نتایج جستجو برای: f 18
تعداد نتایج: 633014 فیلتر نتایج به سال:
Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in Mycobacterium tuberculosis. Despite the emerging importance of quinolones in the treatment of mycobacterial disease, the slow growth and high pathogenicity of M. tuberculosis have precluded direct purification of its gyrase and detailed analysis of quinolone action. To address ...
BACKGROUND The aim of this study was to compare the properties and feasibility of the glucose analog, 2-(18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG), three short (18)F-labeled carboxylic acids, (18)F-fluoroacetate ((18)F-FAC), 2-(18)F-fluoropropionic acid ((18)F-FPA) and 4-((18)F)fluorobenzoic acid ((18)F-FBA), for differentiating tumors from inflammation. METHODS Biodistributions of (18)F-FAC,...
F-18 Fluoride Positron Emission Tomography-Computed Tomography for Detecting Atherosclerotic Plaques
A large number of major cardiovascular events occur in patients due to minimal or some lumen narrowing of the coronary artery. Recent biological studies have shown that the biological composition or vulnerability of the plaque is more critical for plaque rupture compared to the degree of stenosis. To overcome the limitations of anatomical images, molecular imaging techniques have been suggested...
Introduction:Brain imaging with F-18 fluorodeoxyglucose (18F-FDG) positron emission tomography or Tc-99m hexamethylpropyleneamine oxime (99mTc-HMPAO) SPECT is widely used for the evaluation of Alzheimer's dementia (AD); we aim to assess superiority of one method over the other. Methods: Twenty four patients with clinical diagnosi...
A novel synthesis of 4-[(18)F]fluorobenzylamine ([(18)F]FBA) by means of transition metal-assisted sodium borohydride reduction of 4-[(18)F]fluorobenzonitrile ([(18)F]FBN) is described. This approach could successfully be extended to borohydride exchange resin (BER) enabling a viable option for use in automated syntheses. [(18)F]FBA was used for the synthesis of 4-[(18)F]fluorobenzylamine-based...
OBJECTIVES Florbetapir F 18 PET can image amyloid-β (Aβ) aggregates in the brains of living subjects. We prospectively evaluated the prognostic utility of detecting Aβ pathology using florbetapir PET in subjects at risk for progressive cognitive decline. METHODS A total of 151 subjects who previously participated in a multicenter florbetapir PET imaging study were recruited for longitudinal a...
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