Fasciola hepatica, a liver fluke, is a causative agent of fascioliasis in mammals (sheep, cattle, goat, ox and other ruminants, pig, hare rabbit, beaver, elephant, dog, cat and kangaroo). In the unusual hosts, such as man and the horse, the fluke may be found in the lungs, under skin or other situations. The parasite Fasciola hepatica is a hermaphroditic trematode, which is particularly common ...

The surface tegument of the liver fluke Fasciola hepatica is a syncytial cytoplasmic layer bounded externally by a plasma membrane and covered by a glycocalyx, which constitutes the interface between the parasite and its ruminant host. The tegument's interaction with the immune system during the fluke's protracted migration from the gut lumen through the peritoneal cavity and liver parenchyma t...

BACKGROUND fasciola hepatica, along with Fasciola gigantica, is the causative agent of fasciolosis, a foodborne zoonotic disease affecting grazing animals and humans worldwide. Pathology is directly related to the release of parasite proteins that facilitate establishment within the host. The dominant components of these excretory-secretory (ES) products are also the most promising vaccine cand...

The growing availability of sequence information from diverse parasites through genomic and transcriptomic projects offer new opportunities for the identification of key mediators in the parasite-host interaction. Functional genomics approaches and methods for the manipulation of genes are essential tools for deciphering the roles of genes and to identify new intervention targets in parasites. ...

Fasciola hepatica infestation is known to cause bile duct inflammation and biliary obstruction. Endoscopic retrograde cholangiopancreatography shows distinct features in some patients with fascioliasis, but the condition may be overlooked in chronic cases. The endoscopic retrograde cholangiopancreatograpy images must be carefully examined to rule out other possible causes of irregularity and th...

background: the aim of this study was to evaluate the functional capacity of the liver based on the activity of specific enzymes and bilirubin in serum and also to investigate the influence of mechanical and toxic effects of fasciola hepatica on the structures of the blood vessels and biliary tract in the sheep liver. methods: blood samples and liver of 63 indigenous sheep of pramenka breed, sl...

Human fascioliasis (HF), caused by the common liver fluke Fasciola hepatica, is an endemic infection in many parts of tropical countries. HF can also be seen in some of the non-tropical countries. This report describes two girls with severe iron deficiency anemia and eosinophilia, who were diagnosed as HF. The infection was successfully eliminated with the administration of triclabendazole. No ...

A single-step multiplex PCR (here referred to as a duplex PCR) has been developed for simultaneous detection and diagnosis of Fasciola hepatica and F. gigantica. These species overlap in distribution in many countries of North and East Africa and Central and Southeast Asia and are similar in egg morphology, making identification from fecal samples difficult. Based on a comparative alignment of ...

Este estudio se llevó a cabo para establecer la prevalencia e identificar los factores de riesgo asociados con las infestaciones por tremátodos en ganado lechero Holstein el valle Paipa-Boyacá. Las muestras fecales recogidas 100 bovinos seleccionados aleatoriamente examinaron utilizando una técnica sedimentación simple recuento diferencial huevos tremátodos. Se buscaron tres grupos tremátodos, ...

Digestive parasites are a constraint on buffalo productivity. Data regarding the prevalence of parasitic diseases in buffaloes reported developed countries, but Romania, they missing. The aim this study was to evaluate internal raised households and farms from Romania. Faeces samples were collected 180 different ages (calves: 0-6 months; juveniles: 6-30 adults:> 30 months). faecal processed ...