نتایج جستجو برای: facioscapulohumeral muscular dystrophy

تعداد نتایج: 52771  

Journal: :Molecular and cellular biology 2001
K Jo B Rutten R C Bunn D S Bredt

The actinin-associated LIM protein, ALP, is the prototype of a large family of proteins containing an N-terminal PDZ domain and a C-terminal LIM domain. These PDZ-LIM proteins are components of the muscle cytoskeleton and occur along the Z lines owing to interaction of the PDZ domain with the spectrin-like repeats of alpha-actinin. Because PDZ and LIM domains are typically found in proteins tha...

Journal: :Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2012
D H Esposito D O Freedman A Neumayr P Parola

As of 4 November, 2012, 100 patients with an acute muscular Sarcocystis-like illness associated with travel to Tioman Island, Malaysia, have been identified. Thirty-five travelled there mostly during July and August 2011 and 65 mostly during July and August 2012, suggesting an ongoing outbreak. Epidemiological investigations are ongoing. Public health agencies and practicing clinicians should b...

2018
Lindsay M. Wallace Nizar Y. Saad Nettie K. Pyne Allison M. Fowler Jocelyn O. Eidahl Jacqueline S. Domire Danielle A. Griffin Adam C. Herman Zarife Sahenk Louise R. Rodino-Klapac Scott Q. Harper

RNAi emerged as a prospective molecular therapy nearly 15 years ago. Since then, two major RNAi platforms have been under development: oligonucleotides and gene therapy. Oligonucleotide-based approaches have seen more advancement, with some promising therapies that may soon reach market. In contrast, vector-based approaches for RNAi therapy have remained largely in the pre-clinical realm, with ...

2012
Henriëtte Brouwer Chris J M Bartels Arjan Stegeman Gerdien van Schaik

BACKGROUND More and more countries hold databases on cattle movements. The primary purpose of the registration of cattle movements is to provide data for quick tracing of contagious animals in case of disease outbreaks and food safety scares. Nevertheless, these data can also be used for analytical studies to get insight into the nature of the contact structure between and within cattle holding...

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