Aim: Colorectal cancer patients are treated with surgery and sometimes radiotherapy and chemotherapy. Transforming growth factor beta-1 (TGF-β1) acts both as an inhibitor of tumor growth and as a promoter of tumor progression. The aim of this study was to determine the levels of TGF-β1 in plasma in colorectal cancer patients and relate these to the effect of clinicopathological variables. Metho...

BACKGROUND Human idiopathic membranous glomerulonephritis (MGN) has a highly variable clinical course and factors determining its outcome are poorly known. Since transforming growth factor-beta 1 (TGF-beta 1) has an essential role in renal fibrogenesis, we studied the possibility to use urinary excretion of TGF-beta 1 in the assessment of progression of the disease in patients with MGN. METHO...

Background: Vitiligo is characterized by selective destruction of melanocytes. Transforming growth factor beta 1 (TGFβ 1) is the main product of regulatory T cells (Tregs) which are deficient in vitiligo. Thus, lower levels of serum TGFβ 1 are expected in vitiligo. However, TGFβ 1 is a keratinocytederived cytokine with inhibitory effect on melanocyte activity. Thus it may be expected to be high...

BACKGROUND: Sustainable agriculture today plays an important role in the utilization of organic matter and biofertilizers to eliminate or reducing chemical fertilizer, promoting fertility and preserving biological activities, enhancing the health of agricultural products and reducing environmental damage. OBJECTIVES: Current research was conducted to asse...