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Intermediate filaments (IFs) are a major protein component of the detergent-insoluble cytoskeleton. In vertebrates, a growing multigene family encodes these proteins, which have thus far been divided into six subclasses based on protein and DNA structural homologies (Lendahl et al., 1990; reviewed by Steinert and Roop, 1988). Cytoplasmic IFs (classes I-IV, VI) form a 10 nm filamentous network w...

Extension of the en-method from two-dimensional to three-dimensional boundary-layer flows has not been straightforward. Confusion has centred on whether to use temporal or spatial stability theories, conversion between the two approaches, and the choice of integration path. The aim of this study is to clarify the confusion about the direction and magnitude of maximum growth in convectively unst...

The limited capability to regenerate new neurons following injuries of the central neural system (CNS) still remains a major challenge for basic and clinical neuroscience. Neural stem cells (NSCs) could nearly have the potential to differentiate into all kinds of neural cells in vitro. Previous studies verified that exogenous transplanted NSCs are capable of differentiating into neurons and pro...

Intravenous Thrombolysis for Acute Ischemic Stroke After Vitrectomy for Retinal Detachment To the Editor: Once the benefits of intravenous tissue plasminogen activator (tPA) in the treatment of acute ischemic stroke have been proved, it should be interesting to widen its use. We discuss the fact that intravenous thrombolysis with tPA may not be a contraindication to treat an acute ischemic stro...

The earliest possible detection of progressive infantile hydrocephalus requires more detailed standards of normal head size and growth than any previously published. The first part of this communication has been prepared with the object of providing such standards for both full-term and premature babies. There are two distinct ways of collecting growth data. When values are obtained from differ...

James Tanner spent much of his childhood abroad, in the baggage train of the British Army; when he was 9 years old the family returned to their home in east Devon and he began his schooling. He attended Marlborough College from 1934 to 1938 on a scholarship reserved for the sons of Army officers. Having specialised first in modern languages and then in mathematics and engineering, he found hims...

regulation) or hormonal signals indicating satiety, a fulfilling of current nutritional requirements (metabolic Neutral detergent fiber (NDF) is considered the laboratory mearegulation) (Van Soest, 1994). The concentration of sure most closely correlated with voluntary intake of forages by rumiNDF is the most common selection criterion to improve nant livestock. The objectives of this study wer...

The Systolic Blood Pressure Intervention Trial (SPRINT), conducted on older adults with markedly elevated risk for cardiovascular events, demonstrated significant outcome benefit with treatment of blood pressure (BP) to a goal of ≤120/80 mm Hg. Results of the SPRINT trial would not seem generalizable to children and adolescents because the SPRINT focus was on older adults at high risk for cardi...