Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients.

We write to report false-positive results with an alcometer device (Lion S-D2 brand) when it is used in the vicinity of recently applied alcohol disinfectant hand rub. The Orchard Clinic is a medium secure forensic unit set within the grounds of the Royal Edinburgh Hospital. The use of an alcometer is essential in the treatment of Scottish government 'restricted' patients or if there is suspici...

BACKGROUND Most patients with large vessel occlusion (LVO) stroke need to be transferred to receive thrombectomy. To save time, the decision to transfer often relies on clinical scales as a surrogate for LVO rather than imaging. However, clinical scales have been associated with high levels of diagnostic error. The aim of this study is to define the susceptibility to overdiagnosis of our curren...

Positive serum tests for infectious mononucleosis (IM) unaccompanied by the clinical syndrome or blood changes characteristic of the disease were detected in 39/177 (22%) mentally subnormal patients investigated with three different commercially available IM slide tests. Slide positively was still detectable six months later in 27/35 (77%) positive reactors. Positive IM slide tests were signifi...

INTRODUCTION Serum concentrations of acetaminophen are measured to predict the risk of hepatotoxicity in cases of acetaminophen overdose and to identify acetaminophen use in patients with acute liver injury without a known cause. The acetaminophen concentration determines if treatment with N-acetyl cysteine, the antidote for acetaminophen poisoning, is warranted. DESCRIPTION A 49-year-old wom...

Introduction: Diffusion-weighted MR imaging allows for non-invasive investigation of the neural architecture of the brain. In the past decade, several algorithms have been proposed to trace the fiber bundles using a variety of fiber model representations. The simplest and the most widely used model is the diffusion tensor model, with tracts generated by following the principal diffusion directi...