نتایج جستجو برای: familial history

تعداد نتایج: 402168  

2012
George T. Calvert Michael J. Monument Randall W. Burt Kevin B. Jones R. Lor Randall

Extra-abdominal desmoid tumors are a significant cause of morbidity in patients with familial adenomatous polyposis syndrome. Understanding of the basic biology and natural history of these tumors has increased substantially over the past decade. Accordingly, medical and surgical management of desmoid tumors has also evolved. This paper analyzes recent evidence pertaining to the epidemiology, m...

2017

Patient Selection Criteria Coverage eligibility for genetic testing to confirm a diagnosis of familial hypercholesterolemia (FH) will be met when:  Genetic testing is targeted to individuals who are in an uncertain category according to clinical criteria (personal and family history, physical exam, lipid levels), AND  Alternative treatment considerations are in place for individuals who have ...

Journal: :The American journal of psychiatry 1999
Y Hirayasu M E Shenton D F Salisbury J S Kwon C G Wible I A Fischer D Yurgelun-Todd C Zarate R Kikinis F A Jolesz R W McCarley

OBJECTIVE Gray matter volume and glucose utilization have been reported to be reduced in the left subgenual cingulate of subjects with familial bipolar or unipolar depression. It is unclear whether these findings are secondary to recurrent illness or are part of a familial/genetic syndrome. The authors' goal was to clarify these findings. METHOD Volumetric analyses were performed by using mag...

Journal: :AMIA ... Annual Symposium proceedings. AMIA Symposium 2015
Elizabeth S. Chen Genevieve B. Melton Richard Wasserman Paul Rosenau Diantha B. Howard Indra Neil Sarkar

Asthma is the most common chronic childhood disease and has seen increasing prevalence worldwide. While there is existing evidence of familial and other risk factors for pediatric asthma, there is a need for further studies to explore and understand interactions among these risk factors. The goal of this study was to develop an approach for mining, visualizing, and evaluating association rules ...

Journal: :Japanese journal of clinical oncology 2008
Guochun Cao Hongna Lu Jifeng Feng Jian Shu Datong Zheng Yayi Hou

The incidence of lung cancer has been increasing over recent decades. Previous studies showed that polymorphisms of the genes involved in carcinogen-detoxication, DNA repair and cell cycle control comprise risk factors for lung cancer. Recent observations revealed that the growth hormone receptor (GHR) might play important roles in carcinogenesis and Rudd et al. found that the Thr495Pro polymor...

2012
Aikaterini Mantaka Mairi Koulentaki Gregory Chlouverakis Jean Marie Enele-Melono Aikaterini Darivianaki Maria Tzardi Elias A Kouroumalis

BACKGROUND Primary biliary cirrhosis (PBC) is a disease with genetic and environmental pathogenetic background. Chemicals, infectious agents, hormone therapy, reproductive history and surgical interventions have been implicated in the induction of PBC. Familial PBC has been documented in first degree relatives (FDR). Most cohort studies are genetically heterogeneous. Our study aimed to determin...

Journal: :Journal of periodontology 2010
Hyun-Duck Kim Seon-Ju Sim Ja-Young Moon Yoon-Chul Hong Dong-Hun Han

BACKGROUND Several studies suggested that periodontitis is a risk factor for stroke, but the relationship between periodontitis and hemorrhagic stroke has not been widely reported. This study aims to evaluate the association between periodontitis and hemorrhagic stroke and to identify the risk group for this association. METHODS We recruited 165 patients who were diagnosed via computed tomogr...

Journal: :Journal of the National Cancer Institute 2013
Shuji Ogino Reiko Nishihara Paul Lochhead Yu Imamura Aya Kuchiba Teppei Morikawa Mai Yamauchi Xiaoyun Liao Zhi Rong Qian Ruifang Sun Kaori Sato Gregory J Kirkner Molin Wang Donna Spiegelman Jeffrey A Meyerhardt Eva S Schernhammer Andrew T Chan Edward Giovannucci Charles S Fuchs

BACKGROUND Beyond known familial colorectal cancer (CRC) syndromes, the mechanisms underlying the elevated CRC risk associated with CRC family history remain largely unknown. A recent retrospective study suggests familial clustering of CRC with hypomethylation in long interspersed nucleotide element 1 (LINE-1). We tested the hypothesis that CRC family history might confer a higher risk of LINE-...

2011
John L Hopper

Most common diseases demonstrate familial aggregation; the ratio of the risk for relatives of affected people to the risk for relatives of unaffected people (the familial risk ratio)) > 1. This implies there are underlying genetic and/or environmental risk factors shared by relatives. The risk gradient across this underlying 'familial risk profile', which can be predicted from family history an...

2013
Tomasz Waller Roman Nowak Magdalena Tkacz Damian Zapart Urszula Mazurek

BACKGROUND Importance of hereditary factors in the etiology of Idiopathic Scoliosis is widely accepted. In clinical practice some of the IS patients present with positive familial history of the deformity and some do not. Traditionally about 90% of patients have been considered as sporadic cases without familial recurrence. However the exact proportion of Familial and Sporadic Idiopathic Scolio...

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